Hannig G

No ORCID on file · 2 papers in corpus · active 2019-2022

Study types

  • article 1

Condition tags

  • endometriosis 1
  • chronic_pelvic_pain 1
2022
Guanylate cyclase-C agonists as peripherally acting treatments of chronic visceral pain.
Trends in pharmacological sciences ·doi:10.1016/j.tips.2021.11.002

Irritable bowel syndrome (IBS) is a chronic gastrointestinal disorder characterized by abdominal pain and altered bowel habit that affects ~11% of the global population. Over the past decade, preclinical and clinical studies have revealed a…

article 2019
Linaclotide treatment reduces endometriosis-associated vaginal hyperalgesia and mechanical allodynia through viscerovisceral cross-talk
Pain ·doi:10.1097/j.pain.0000000000001657

Endometriosis, an estrogen-dependent chronic inflammatory disease, is the most common cause of chronic pelvic pain. Here, we investigated the effects of linaclotide, a Food and Drug Administration-approved treatment for IBS-C, in a rat mode…