Alison Murray

No ORCID on file · 6 papers in corpus · active 2014-2021

Study types

  • article 6

Condition tags

  • endometriosis 2
  • adenomyosis 2
article 2021
Markers of human endometrial hypoxia can be detected in vivo and ex vivo during physiological menstruation
Human Reproduction ·doi:10.1093/humrep/deaa379

STUDY QUESTION: Can markers of human endometrial hypoxia be detected at menstruation in vivo? SUMMARY ANSWER: Our in vivo data support the presence of hypoxia in menstrual endometrium of women during physiological menstruation. WHAT IS KNOW…

article 2021
Obesity is associated with heavy menstruation that may be due to delayed endometrial repair
·doi:10.1530/joe-20-0446

Heavy menstrual bleeding is common and debilitating but the causes remain ill defined. Rates of obesity in women are increasing and its impact on menstrual blood loss (MBL) is unknown. Therefore, we quantified BMI and MBL in women not takin…

article 2021
The endometrial response to modulation of ligand-progesterone receptor pathways is reversible
Fertility and sterility ·doi:10.1016/j.fertnstert.2021.02.008

ObjectiveTo study the impact of the progesterone receptor modulator (PRM), ulipristal acetate (UPA), on endometrial morphology and function.DesignCross-sectional.SettingUniversity Research Institute.Patient(s)Endometrial biopsies from 16 pa…

article 2018
Hypoxia and hypoxia inducible factor-1α are required for normal endometrial repair during menstruation
·doi:10.1038/s41467-017-02375-6

Heavy menstrual bleeding (HMB) is common and debilitating, and often requires surgery due to hormonal side effects from medical therapies. Here we show that transient, physiological hypoxia occurs in the menstrual endometrium to stabilise h…

article 2014
A Novel Mouse Model of Endometriosis Mimics Human Phenotype and Reveals Insights into the Inflammatory Contribution of Shed Endometrium
The American journal of pathology ·doi:10.1016/j.ajpath.2014.03.011
article 2014
Evidence from a Mouse Model That Epithelial Cell Migration and Mesenchymal-Epithelial Transition Contribute to Rapid Restoration of Uterine Tissue Integrity during Menstruation
·doi:10.1371/journal.pone.0086378

BACKGROUND: In women dynamic changes in uterine tissue architecture occur during each menstrual cycle. Menses, characterised by the shedding of the upper functional layer of the endometrium, is the culmination of a cascade of irreversible c…