Myrella L. Cruz

Estrogen stimulates corticotropin-releasing hormone (CRH) expression in endometrial tissue, and CRH signaling contributes to inflammation and pain, suggesting a mechanistic role in endometriosis pathophysiology. We previously identified ele…

Endometriosis is a chronic gynecological disease defined by the presence of endometrial tissue outside the uterine cavity, causing symptoms such as dysmenorrhea, chronic pelvic pain, and infertility. Voluntary physical activity has been pro…

Endometriosis is a gynecological disorder characterized by growth of endometrial tissue outside the uterine cavity, with symptoms which may include chronic pelvic pain and infertility resulting in a decreased quality of life. Previous studi…

BACKGROUND: Endometriosis is a complex gynecological disorder characterized by the ectopic growth of endometrial tissue. Symptoms of endometriosis are known to impair the quality of life of patients, and among these are found dysmenorrhea, …

Endometriosis is a gynecological disorder characterized by the growth of endometrial tissue in areas outside the uterus. Previous studies in our laboratory demonstrated that endometriosis animals have increased mesenteric adipose tissue (MA…

Introduction Endometriosis is a complex gynecological disorder characterized by the ectopic growth of endometrial tissue. Symptoms of endometriosis are known to impair the quality of life of patients, among these symptoms are dysmenorrhea, …

Endometriosis, an estrogen dependent disease, is a gynecological disorder characterized by the growth of endometrial tissue outside the uterine cavity resulting in pain and discomfort. Estrogen plays an important role in the growth and pers…

Endometriosis is a chronic gynecological disorder characterized by peritoneal inflammation, infertility, chronic pelvic pain, fibrosis, and growth of endometrial tissue outside the endometrial cavity. In previous studies we found that expos…

Endometriosis is a complex gynecological disease characterized by the growth of endometrial tissue outside of the uterine cavity. Some symptoms that are prevalent in women with endometriosis are dysmenorrhea, infertility, pelvic pain, and g…

UNLABELLED: Endometriosis is a chronic gynecological disorder characterized by the growth of endometrial glands and stroma outside the endometrial cavity producing inflammation and pain. Previously we demonstrated that modulation of the hyp…

A physically active lifestyle has been shown to confer preventive health benefits in many chronic conditions, in part by enhancing immunological health. Prolonged moderate exercise increases secretion of IL‐6 that may also promote secretion…

Endometriosis, a gynecological disorder, is characterized by increased levels of the estrogen receptor β (ERβ) in endometrial tissue. Estrogen receptors (ER) are also present in visceral fat and dysregulation of their function is known to c…

Endometriosis is a chronic inflammatory condition caused by migration of endometrial tissue outside the uterine cavity resulting in dysmenorrhea, chronic pelvic pain and infertility. Current hormonal or surgical treatments for this debilita…

Peripheral inflammation produces an immune response in the brain by the activation of microglia and astrocytes. Astrocytes are also involved in the pain symptoms of chronic diseases such as endometriosis, which is characterized by the growt…

Endometriosis is a chronic gynecological disorder defined as the presence of endometrial glands and stroma outside the endometrial cavity. This condition is characterized by peritoneal inflammation, fibrosis, adhesions and ovarian cysts, wh…

Endometriosis is a gynecological chronic condition caused by endometrial tissue migration outside of the uterine cavity. Some symptoms associated with this inflammatory disease are chronic pelvic pain, infertility and painful menstrual cycl…

Introduction Endometriosis is a gynecological disorder in which tissue that normally lines the endometrium grows outside the uterus and commonly results in peritoneal inflammation and infertility. Our previous studies show that stress exace…

Endometriosis is characterized by endometrial tissue growing in areas outside the reproductive system resulting in discomfort, pain, and infertility. Environmental factors such as stress have been suggested to exacerbate the condition, and …

Although the role of vitamin D in endometriosis is still unclear, vitamin D signaling through the vitamin D receptor (VDR) is associated with anti‐proliferative and anti‐inflammatory effects. We previously reported differential VDR expressi…

Prior studies from our laboratory have shown that stress can exacerbate the severity of endometriosis, a chronic gynecological disorder. The vitamin D receptor (VDR), expressed in cycling endometrium, is associated with anti-proliferative a…

BACKGROUND: Symptoms of endometriosis, such as pain and infertility, are considered significant sources of stress. In many chronic conditions, exercise can act as a stress buffer and influence pain perception. We tested the impact of swimmi…