Rômulo Medina de Mattos

article 2019

Galectin-3 plays an important role in endometriosis development and is a target to endometriosis treatment

Molecular and cellular endocrinology ·doi:10.1016/j.mce.2019.02.007

This study aimed to analyze galectin-3 importance in endometriotic lesions development and the effect of recombinant Gal-3 carbohydrate recognition domain (Gal3C) in experimental endometriosis treatment. Experimental endometriosis was induc…

article 2017

Anti‐inflammatory effects of Tibouchina granulosa in experimental model of endometriosis

·doi:10.1096/fasebj.31.1_supplement.1068.8

Tibouchina granulosa is an ornamental tree commonly found in Brazil and some species of the genus are used in popular medicine. Researches from our group have shown that the tea from the leaves present a significant wound healing effect and…

article 2016

Aberrant levels of Wnt/β-catenin pathway components in a rat model of endometriosis.

Histology and histopathology ·doi:10.14670/hh-11-730

Endometriosis is a benign gynecological disease affecting approximately 10-15% of women of reproductive age and 25-50% of all infertile women. It is characterized by the presence of glands and/or endometrial stroma outside the uterine cavit…

article 2015

The oil-resin of the tropical rainforest tree Copaifera langsdorffii reduces cell viability, changes cell morphology and induces cell death in human endometriotic stromal cultures

The Journal of pharmacy and pharmacology ·doi:10.1111/jphp.12479

OBJECTIVES: The hormonal treatment for endometriosis frequently fails to completely eradicate endometriotic implants. A new therapeutic treatment is needed. This study investigates the in-vitro effect of Copaifera langsdorffii oil-resin on …