Jiaming Zhang

No ORCID on file · 3 papers in corpus · active 2021-2025

Study types

  • article 2

Condition tags

  • endometriosis 2
article 2025
Harmine inhibits oxidative phosphorylation, thus regulating the polarization of macrophages mediated by extracellular adenosine in endometriosis
Human Reproduction ·doi:10.1093/humrep/deaf130

STUDY QUESTION: Can harmine mitigate endometriosis by modulating oxidative phosphorylation (OXPHOS) suppression and macrophage polarization? SUMMARY ANSWER: Harmine induces apoptosis in endometriotic lesions by inhibiting OXPHOS while also…

2022
Cartilage Oligomeric Matrix Protein, Diseases, and Therapeutic Opportunities.
International journal of molecular sciences ·doi:10.3390/ijms23169253

Cartilage oligomeric matrix protein (COMP) is an extracellular matrix (ECM) glycoprotein that is critical for collagen assembly and ECM stability. Mutations of COMP cause endoplasmic reticulum stress and chondrocyte apoptosis, resulting in …

article 2021
Target identification and drug discovery by data-driven hypothesis and experimental validation in ovarian endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2021.01.027

ObjectiveTo identify targets and discover drugs for ovarian endometriosis (OE) DESIGN: A basic study based on a data-driven hypothesis and experimental validation SETTING: Center for Reproductive Medicine PATIENT(S)/ANIMAL(S): Fourteen pati…