Wright JA

No ORCID on file · 5 papers in corpus · active 1995-2012

Study types

  • article 3
  • other 2

Condition tags

  • endometriosis 4
other 2012
Modulation of hepatocyte growth factor secretion in human female reproductive tract stromal fibroblasts by poly (I:C) and estradiol
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.2011.01063.x

PROBLEM: Hepatocyte Growth Factor (HGF) secretion facilitates epithelial cell growth and development in the female reproductive tract (FRT) and may contribute to pathological conditions such as cancer and endometriosis. We hypothesized that…

article 2009
Estradiol modulation of hepatocyte growth factor by stromal fibroblasts in the female reproductive tract
Fertility and sterility ·doi:10.1016/j.fertnstert.2008.10.047

Primary human uterine, cervical, and ectocervical stromal fibroblasts constitutively secrete hepatocyte growth factor (HGF), yet only uterine stromal fibroblasts increase HGF secretion in response to estradiol. Estradiol-induced HGF secreti…

article 1998
Gonadotropin-Releasing Hormone Agonist (GnRH-a) Therapy Alters Activity of Plasminogen Activators, Matrix Metalloproteinases, and Their Inhibitors in Rat Models for Adhesion Formation and Endometriosis: Potential GnRH-a–Regulated Mechanisms Reducing Adhesion Formation
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00032-6

ObjectiveTo evaluate the effects of a gonadotropin-releasing hormone agonist (GnRH-a) on plasminogen activator (PA), matrix metalloproteinase (MMP), plasminogen activator inhibitor (PAI) and matrix metalloproteinase inhibitor (MMPI) activit…

other 1995
Gonadotropin-releasing hormone agonist therapy reduces postoperative adhesion formation and reformation after adhesiolysis in rat models for adhesion formation and endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)57554-2

OBJECTIVES: To evaluate the effectiveness of GnRH agonist (GnRH-a) therapy on adhesion formation and reformation in established rat models for surgically induced adhesion formation and endometriosis. DESIGN: Before surgery, female Sprague-…

article 1995
Partial purification and amino acid sequence analysis of endometriosis protein-II (ENDO-II) reveals homology with tissue inhibitor of metalloproteinases-1 (TIMP-1).
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.80.12.8530636

De novo synthesized endometriosis protein-II (ENDO-II; M(r) 28,000 to 32,000; pI 7.0 to 9.0) was partially purified from rat endometriotic tissue culture media using affinity chromatography and two-dimensional SDS-PAGE. The protein was elec…