BackgroundSyndrome differentiation in Traditional Chinese Medicine (TCM) is pivotal to clinical practice and dictates the efficacy of medicinal treatments. However, precision diagnostic models for TCM syndromes, constructed from biomarkers …
PURPOSE: To systematically evaluate and compare the quality, readability, and query-model consistency of adenomyosis-related content generated by two large language models, ChatGPT (GPT-5) and DeepSeek (R1). MATERIALS AND METHODS: In total…
ObjectivesThis study aims to evaluate the safety and efficacy of ovarian vein embolization combined with polidocanol sclerotherapy for Venous-origin chronic pelvic pain (VO-CPP) and to elucidate potential risk factors affecting prognosis.Me…
BackgroundInfertility is a major global health burden, yet scalable lifestyle strategies to improve reproductive outcomes remain limited. Exercise is low cost and biologically plausible, but evidence on its association with fertility-relate…
BackgroundThe global burden of kidney stones is increasing, while di(2-ethylhexyl) phthalate (DEHP), a widespread plasticizer and endocrine-disrupting pollutant, has been implicated as a potential environmental risk factor. This study inves…
OBJECTIVE: Approximately 20% of adenomyosis cases occur in women under 40 years of age [1]. Although LNG-IUD is the first-line medical therapy, its treatment failure is closely associated with uterine volume [2] with expulsion rates reporte…
BACKGROUND: Direct comparative data on postoperative sexual function between laparoscopic total hysterectomy (LTH) and high-intensity focused ultrasound (HIFU) in adenomyosis (AM) remain limited; therefore, this retrospective study compared…
BackgroundSalpingitis infertility (SI) is a common disease among women of childbearing age, referring secondary infertility caused by acute or chronic salpingitis. Ginsenoside Rb1 (Rb1) has been confirmed to be an effective drug agent SI. N…
BACKGROUND: Device expulsion is a common complication of the levonorgestrel-releasing intrauterine system (LNG-IUS), with a higher incidence among high-risk patients presenting with enlarged uterine cavities, cervical laxity or menorrhagia.…
Despite ongoing challenges in developing effective non-surgical and non-hormonal treatments for endometriosis, the psychological manifestations of the disease-particularly anxiety-remain comparatively underexplored. In this study, a hydroge…
OBJECTIVE: To evaluate the association of high-intensity focused ultrasound (HIFU) combined with syndrome differentiation-based individualized traditional Chinese medicine (TCM) herbal therapy with 12-month clinical outcomes compared with H…
BACKGROUND: Endometriosis (EMs) is a common gynecological disorder characterized by ectopic endometrial tissue growth, leading to chronic inflammation and pelvic pain. Despite its high prevalence, the molecular mechanisms underlying EMs rem…
Hydrogels are highly hydrated three-dimensional polymeric network materials that have attracted considerable attention in medical and biomedical fields owing to their favorable chemical modifiability, physical tunability, biocompatibility, …
ObjectiveTo identify and characterize distinct types of authoritative cardiology-related key opinion leaders (ACKOLs) on Xiaohongshu and examine their communication characteristics and engagement patterns.MethodsA social media profiling stu…
BACKGROUND: Cervical cancer (CC) is a significant global health threat for women worldwide. Although IKBIP has been recognized as an oncogene, little is known about its contribution to CC. Therefore, we aimed to analyze IKBIP expression, it…
STUDY QUESTION: Does PIEZO1 play any role in adenomyosis-associated dysmenorrhea? SUMMARY ANSWER: PIEZO1 downregulation in the myometrium reduces the expression of endothelial nitric oxide synthase (eNOS) and nitric oxide (NO) production, …
Metabolic dysfunction-associated steatotic liver disease (MASLD) is highly prevalent and associated with metabolic dysfunction, systemic inflammation, and increased cardiovascular risk. The C-reactive protein-Triglyceride-Glucose Index (CTI…
BackgroundIntrauterine adhesions (IUA) are fibrotic scars that impair endometrial regeneration, and compromise fertility. Emerging evidence implicates circular RNAs (circRNAs) in fibrotic remodeling, but it remains unclear how the circRNA l…
BACKGROUND: Ovarian endometriosis (OE) is a leading cause of female infertility. Our previous work identified iron overload-driven oxidative stress and mitochondrial dysfunction in granulosa cells as key pathogenic features, yet the mechani…
BACKGROUND: The optimal surgical approach for reconstructing abdominal wall defects after radical resection of abdominal wall endometriosis (AWE) remains debated. This study aimed to compare the perioperative safety, recovery outcomes, and …
ObjectiveTo evaluate the efficacy and safety of LED red light therapy in alleviating primary dysmenorrhea.MethodsA total of 119 patients with primary dysmenorrhea were enrolled in 2022. The intervention was LED red light therapy administere…
This study aimed to explore the association between leukocyte telomere length (LTL) and premature rupture of membranes (PROM). This cross-sectional study included a total of 170,841 participants from the UK Biobank. Restricted cubic spline …
Cardiovascular and cerebrovascular diseases (CVDs) are closely associated with disturbances in vascular homeostasis, including endothelial dysfunction, abnormal vascular remodeling, inflammation, oxidative stress, thrombosis, barrier disrup…
BACKGROUND: Endometriosis affects approximately 10% of reproductive-age women, with a diagnostic delay of 7-10 years. Despite clinical heterogeneity, current rASRM staging poorly predicts treatment outcomes. Molecular subtyping may reveal b…
Acute respiratory failure (ARF) is a common organ failure in acute pancreatitis (AP) with high mortality. This study used machine learning to predict ARF risk in AP patients through a retrospective, multicenter cohort analysis involving MIM…