Rytkönen KT

No ORCID on file · 4 papers in corpus · active 2019-2022

Study types

  • article 2
  • other 1
  • preprint 1

Condition tags

  • endometriosis 3
  • adenomyosis 1
article 2022
Histone H3K4me3 breadth in hypoxia reveals endometrial core functions and stress adaptation linked to endometriosis
iScience ·doi:10.1016/j.isci.2022.104235

Trimethylation of histone H3 at lysine 4 (H3K4me3) is a marker of active promoters. Broad H3K4me3 promoter domains have been associated with cell type identity, but H3K4me3 dynamics upon cellular stress have not been well characterized. We …

article 2022
Overexpression of Human Estrogen Biosynthetic Enzyme Hydroxysteroid (17beta) Dehydrogenase Type 1 Induces Adenomyosis-like Phenotype in Transgenic Mice
International journal of molecular sciences ·doi:10.3390/ijms23094815

Hydroxysteroid (17beta) dehydrogenase type 1 (HSD17B1) is an enzyme that converts estrone to estradiol, while adenomyosis is an estrogen-dependent disease with poorly understood pathophysiology. In the present study, we show that mice unive…

other 2020
Transcriptomic responses to hypoxia in endometrial and decidual stromal cells
Reproduction (Cambridge, England) ·doi:10.1530/REP-19-0615

Human reproductive success depends on a properly decidualized uterine endometrium that allows implantation and the formation of the placenta. At the core of the decidualization process are endometrial stromal fibroblasts (ESF) that differen…

preprint 2019
Transcriptomic responses to hypoxia in endometrial and decidual stromal cells
·doi:10.1101/2019.12.21.885657

Abstract Human reproductive success depends on a properly decidualized uterine endometrium that allows implantation and the formation of the placenta. At the core of the decidualization process are endometrial stromal fibroblasts (ESF) that…