Coutinho EM

No ORCID on file · 13 papers in corpus · active 1973-2012

Study types

  • article 10
  • other 2
  • review 1

Condition tags

  • endometriosis 7
  • adenomyosis 5
  • dysmenorrhea 1
  • dyspareunia 1
article 2012
Effect of a hormone-releasing intrauterine system (Mirena®) on aromatase and Cox-2 expression in patients with adenomyosis submitted or not, to endometrial resection

Hugo Maia Jr1,2, Clarice Haddad1, Julio Casoy1, Rebeca Maia1, Nathanael Pinheiro3, Elsimar M Coutinho11Centro de Pesquisa e Assistência em Reprodução Humana (CEPARH), 2Itaigara Memorial Day Hospital, 3IMAGEPA…

article 2012
Effect of a hormone-releasing intrauterine system (Mirena®) on aromatase and Cox-2 expression in patients with adenomyosis submitted or not, to endometrial resection
International journal of women's health ·doi:10.2147/ijwh.s30087

OBJECTIVE: To investigate the effect of a levonorgestrel-releasing intrauterine system (Mirena(®)) on aromatase and cyclooxygenase-2 (Cox-2) expression in the endometrium of patients with adenomyosis who were submitted to endometrial resect…

article 2008
Effect of oral contraceptives on vascular endothelial growth factor, Cox-2 and aromatase expression in the endometrium of uteri affected by myomas and associated pathologies
Contraception ·doi:10.1016/j.contraception.2008.07.002

BackgroundThe study was conducted to evaluate vascular endothelial growth factor (VEGF), Cox-2 and aromatase expression in the endometrium of uteri with myomas and other associated pathologies.Study designHysteroscopy was performed in 118 w…

article 2005
Effect of menstrual cycle and hormonal treatment on ki-67 and bcl-2 expression and adenomyosis
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590400021086

OBJECTIVE: To study the expression of proliferation markers (ki-67) and anti-apoptotic protein (bcl-2) in adenomyotic lesions during the menstrual cycle or following the use of steroid hormones. PATIENTS AND METHODS: Ninety patients of repr…

other 2004
Proliferation kinetics in adenomyosis during the menstrual cycle and during oral contraceptive use
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology ·doi:10.1080/09513590310001652982

Our objective was to investigate the presence of focal p53 expression in relation to proliferation rates in adenomyotic lesions during the menstrual cycle and in women on oral contraception. Fifty-nine perimenopausal patients with menorrhag…

article 2003
Insertion of Mirena after Endometrial Resection in Patients with Adenomyosis
The Journal of the American Association of Gynecologic Laparoscopists ·doi:10.1016/s1074-3804(05)60158-2

Study objectiveTo evaluate the efficacy of Mirena, a levonorgestrel-releasing intrauterine device, after endometrial resection for treatment of menorrhagia caused by adenomyosis.DesignOpen, randomized, observational study (Canadian Task For…

article 2001
IS MENSTRUATION NORMAL? SUPPRESSION OF THE MENSTRUAL CYCLE IN CLINICAL PRACTICE
·doi:10.1017/s0962279901000357

According to Webster's Universal College Dictionary (Random House, 1997), normal means “conforming to the standard or the common type; usual regular, natural; free of any mental disorder; sane; free from disease or malformation”. On the bas…

article 1996
Evaluation of ovarian endometriotic cysts by transvaginal sonography and videolaparoscopy
·doi:10.1016/s1074-3804(96)80226-x

Transvaginal sonography made a preoperative diagnosis of ovarian endometriotic cyst in 45 women (age 20-45 yrs). The cyst was unilocular in 37 patients and multilocular in the rest. Intracystic projections were noted in seven. Doppler studi…

review 1990
Therapeutic experience with gestrinone
Progress in clinical and biological research
other 1988
Treatment of endometriosis by vaginal administration of gestrinone
Fertility and Sterility ·doi:10.1016/s0015-0282(16)59765-9

The effectiveness and acceptability of gestrinone administered by vaginal route was evaluated in a group of 110 patients with endometriosis. Patients were divided into four groups. The first three groups were treated by vaginal route. Group…

article 1982
Treatment of endometriosis with gestrinone (R-2323), a synthetic antiestrogen, antiprogesterone
American Journal of Obstetrics and Gynecology ·doi:10.1016/0002-9378(82)90180-6

Twenty patients with endometriosis diagnosed by laparoscopy were treated with the antiestrogen, antiprogesterone gestrinone (R-2323) for 6 to 8 months. The drug was administered in a dose of 5 mg twice weekly. According to the American Fert…

article 1975
Effects of aminophylline, imidazole and indomethacin on spontaneous and prostaglandin induced ovarian contractions in vitro.

Imidazole, acetylcholine, phenylephrine prostaglandin F2alpha, and methyl prostaglandin F2alpha increased the contractility of guinea pig and human ovaries in vitro. This effect was suppressed by aminophylline. Indomethacin inhibited ovaria…

article 1973
The effect of a continuous low dose progestin on tubal and uterine motility.

The pattern of tubal and uterine motility was investigated in 16 women treated with 350 mcs megestrol acetate daily for 4 weeks. Myometrial activity characteristic of estrogen domination was recorded during the proliferative phase in most p…