Julie A W Stilley

No ORCID on file · 6 papers in corpus · active 2008-2020

Study types

  • review 3
  • article 2
  • other 1

Condition tags

  • endometriosis 6
  • infertility 4
review 2020
Identifying Mechanisms of Endometriosis-Associated Reduced Fecundity in a Rat Model: Novel Insights toward Understanding Human Infertility
Advances in anatomy, embryology, and cell biology ·doi:10.1007/978-3-030-51856-1_2
review 2020
Introduction to Preclinical Evidence from Animal Models of Endometriosis
Advances in anatomy, embryology, and cell biology ·doi:10.1007/978-3-030-51856-1_1

Endometriosis, the presence and growth of uterine endometrial glandular epithelial and stroma cells outside the uterine cavity, causes pain and infertility in women and girls of reproductive age. As randomized, double-blinded, controlled st…

review 2012
Cellular and molecular basis for endometriosis-associated infertility
Cell and tissue research ·doi:10.1007/s00441-011-1309-0

Endometriosis is a gynecological disease characterized by the presence of endometrial glandular epithelial and stromal cells growing in the extra-uterine environment. The disease afflicts 10%-15% of menstruating women causing debilitating p…

article 2011
TIMP1 Contributes to Ovarian Anomalies in Both an MMP-Dependent and -Independent Manner in a Rat Model1
Biology of reproduction ·doi:10.1095/biolreprod.111.094680

Ovulatory dysfunction occurs in women with endometriosis, yet the mechanisms are unknown. We have shown that endometriotic lesions synthesize and secrete tissue inhibitor of metalloproteinase (TIMP) 1 into the peritoneal cavity in humans an…

other 2010
Neutralizing TIMP1 restores fecundity in a rat model of endometriosis and treating control rats with TIMP1 causes anomalies in ovarian function and embryo development
Biology of reproduction ·doi:10.1095/biolreprod.109.083287

Human and rat endometriotic lesions synthesize and secrete tissue inhibitor of metalloproteinase 1 (TIMP1). More TIMP1 localizes in the ovarian theca in an established rat model for endometriosis (Endo) when compared to surgical controls (S…

article 2008
Reduced Fecundity in Female Rats with Surgically Induced Endometriosis and in Their Daughters: A Potential Role for Tissue Inhibitors of Metalloproteinase 11
Biology of reproduction ·doi:10.1095/biolreprod.108.073411

The cause of reduced fecundity in women with endometriosis is unknown. Expression of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) by both ectopic and eutopic endometrium reportedly has a role in the p…