Hui Li

Per- and polyfluoroalkyl substances (PFAS) have been previously associated with polycystic ovary syndrome (PCOS). However, the health effects of emerging PFAS alternatives on PCOS remain unclear. This study aims to examine the associations …

STUDY QUESTION: What is the current landscape of randomized controlled trials (RCTs) evaluating stem cell-based therapies for women's reproductive diseases, and how effectively has preclinical research informed their clinical translation? …

OBJECTIVE: High-intensity focused ultrasound (HIFU) therapy is increasingly used in the management of various solid tumors. However, limited data are available regarding the association between HIFU treatment and coagulation function. MATE…

Acute pancreatitis (AP) is a common, potentially severe inflammatory disease of the pancreas. Although environmental triggers such as alcohol and gallstones are well known, only a subset of exposed individuals develop AP, suggesting that ge…

Vasohibin-1 (VASH-1) is an endothelial protein that serves as a negative feedback regulator of angiogenesis. Through its microtubule carboxypeptidase activity, VASH-1 plays a key role in vascular homeostasis. While previous studies have inv…

Abstract Study question Can a standardised hospital-school collaborative model improve early detection and multidisciplinary management of adolescent dysmenorrhea and suspected early-onset endometriosis? Summary answer Yes, this model signi…

OBJECTIVE: By using the propensity score matching (PSM) method, this study compared the pregnancy outcomes of two ovulation induction regimens, clomiphene citrate (CC) and letrozole (LE), in intrauterine insemination (IUI) cycles. It aimed …

Unexplained recurrent pregnancy loss (URPL) represents a prevalent obstetric complication and remains a challenging condition with poorly understood genetic etiology. Through whole-exome sequencing of 94 URPL patients, we identified enriche…

AIM: To systematically assess the prevalence of sexual dysfunction among patients suffering from endometriosis. METHODS: A literature search was carried out using databases such as PubMed, Web of Science, CNKI, and Wanfang from the incepti…

BACKGROUND: This study aimed to compare reproductive and obstetric outcomes between frozen embryo transfer (FET) cycles using letrozole combined with human menopausal gonadotropin (HMG) for ovulation induction (OI) and hormone replacement t…

Polycystic ovary syndrome (PCOS) exacerbated by obesity represents a complex intersection of endocrine and immune dysregulation, significantly impairing reproductive and metabolic health. This characterizes the immune-inflammatory landscape…

BACKGROUND: The atypical hemolytic uremic syndrome (aHUS) presents diagnostic and therapeutic challenges due to overlapping features with other conditions like Preeclampsia/HELLP syndrome and thrombotic thrombocytopenic purpura (TTP). Pregn…

In this single-center, double-blinded, randomized controlled trial, we investigated whether human umbilical cord-derived mesenchymal stromal cells loaded collagen scaffolds (hUC-MSC/CS) could improve the cumulative live-birth rate (cLBR) in…

BACKGROUND: Endometriosis (EMs) is a common condition that causes dysmenorrhea, chronic pelvic pain, and infertility, affecting millions of women worldwide. Despite the use of assisted reproductive technology, EMs patients often experience …

PURPOSE: To assess the effectiveness of personalized embryo transfer (pET) in enhancing intrauterine pregnancy rates in women with polycystic ovary syndrome (PCOS) without recurrent implantation failure (RIF). METHODS: This single-center, …

PURPOSE: Hydrosalpinx reduces the pregnancy outcomes of in vitro fertilization and embryo transfer (IVF-ET). Tubal occlusion has been shown to improve IVF-ET success; however, the optimal timing of oocyte retrieval and the molecular changes…

BACKGROUND AND AIMS: This network meta-analysis aimed to compare the perioperative efficacy of various minimally invasive hysterectomy procedures for treating benign gynecological diseases and to assess whether vaginal natural orifice trans…

RATIONALE: Ichthyosis uteri is a rare pathological condition characterized by the replacement of the endometrial lining by stratified squamous epithelium. Yet its occurrence with endometrial adenocarcinoma is very rare. PATIENT CONCERNS: A…

BACKGROUND: Afferent neuronal hypersensitization via P2X3 receptor signaling has been implicated as a driver of several disorders, including refractory chronic cough, endometriosis, diabetic neuropathic pain, and overactive bladder. Eliapix…

Previous ultrasound studies suggest that patients with adenomyosis (AM) exhibit increased uterine cavity stiffness, although direct evidence regarding extracellular matrix (ECM) content and its specific impact on endometrial stiffness remai…

OBJECTIVE: Endometriosis (EMS) is an estrogen-dependent condition with unclear pathogenesis. Recent findings suggest implicate autophagy and ferroptosis in EMS development. METHODS: We assessed autophagy and ferroptosis proteins in EMS pat…

BACKGROUND: Embryo implantation in a receptive endometrium is crucial for successful pregnancy. Endometrial receptivity (ER) prediction tools based on endometrial transcriptome biomarkers by endometrial biopsy have been used to guide succes…

OBJECTIVE: To investigate the outcome of total laparoscopic hysterectomy (TLH) and postoperative pain characteristics and compare the pain severity after TLH for adenomyosis or uterine fibroids. METHODS: This prospective observational stud…

Gastric cancer is one of the most common malignancies. Although some patients benefit from immunotherapy, the majority of patients have unsatisfactory immunotherapy outcomes, and the clinical significance of immune-related genes in gastric …