Sakamoto N

No ORCID on file · 3 papers in corpus · active 2011-2020

Study types

  • other 1

Condition tags

  • endometriosis 1
other 2020
Oncogenic mutation in RAS-RAF axis leads to increased expression of GREB1, resulting in tumor proliferation in colorectal cancer
Cancer science ·doi:10.1111/cas.14558

BRAFV600E mutation accounts for up to 90% of all BRAF mutations in human colorectal cancer (CRC), and constitutively activates the MEK-MAPK pathway. It is recognized that neutralizing mAbs for epidermal growth factor receptor alone are not …

2012
Reg IV is a direct target of intestinal transcriptional factor CDX2 in gastric cancer.
PloS one ·doi:10.1371/journal.pone.0047545

REG4, which encodes Reg IV protein, is a member of the calcium-dependent lectin superfamily and potent activator of the epidermal growth factor receptor/Akt/activator protein-1 signaling pathway. Several human cancers overexpress Reg IV, an…

2011
Serum concentration and expression of Reg IV in patients with esophageal cancer: Age-related elevation of serum Reg IV concentration.
Oncology letters ·doi:10.3892/ol.2011.239

Regenerating islet-derived family, member 4 (REG4, which encodes Reg IV) is a marker for cancer and inflammatory bowel disease. This study aimed to investigate the diagnostic utility of Reg IV measurement in sera from esophageal cancer pati…