Melton LJ 3rd

ObjectiveTo compare the risk of subsequent oophorectomy among women who underwent hysterectomy for benign indications and those who did not.MethodsUsing Rochester Epidemiology Project resources, we compared the risk of oophorectomy through …

Background & aimsAge, diarrhea, and certain chronic illnesses are risk factors for fecal incontinence (FI). However, the contribution of obstetric injury to the development of FI later in life is unclear. We sought to better understand the …

ObjectiveTo investigate the mortality associated with cardiovascular diseases and the effect of estrogen treatment in women who underwent unilateral or bilateral oophorectomy before menopause.DesignWe conducted a cohort study with long-term…

In the Mayo Clinic Cohort Study of Oophorectomy and Aging, women who had both ovaries removed before reaching natural menopause experienced a long-term increased risk of parkinsonism, cognitive impairment or dementia, and depressive and anx…

ObjectiveHaving demonstrated that prior history of prolapse was a risk factor for pelvic floor repair procedures after hysterectomy, the objective of this study was to assess medical risk factors for pelvic floor repair after hysterectomy.M…

To describe trends in the utilization of surgical procedures for pelvic organ prolapse among women in Olmsted County, MN, we retrospectively identified all county residents undergoing pelvic organ prolapse repair from January 1, 1965 throug…

ObjectiveThe purpose of this study was to assess temporal trends for hysterectomy among Olmsted County, Minnesota women.Study designUsing the Rochester Epidemiology Project database, we identified all county residents undergoing a hysterect…

ObjectiveTo assess long-term fracture risk after hysterectomy, with or without oophorectomy.DesignPopulation-based, cohort study.SettingOlmsted County, Minnesota.Patient(s)Women residing in Olmsted County (n = 9,258) who underwent hysterect…

ObjectiveTo determine whether women with pelvic endometriosis are at increased fracture risk.DesignHistorical cohort study.SettingPopulation-based investigation using the data resources of the Rochester Epidemiology Project.Patient(s)From O…

OBJECTIVE: We examined whether widespread use of laparoscopy was accompanied by increased diagnosis of asymptomatic endometriosis, inflated rates of diagnosis, or changes in the clinical spectrum of disease. DESIGN: Population-based cohort…

Houston, Diana E. PhD; Noller, Kenneth L. MD; Melton, L Joseph III MD; Selwyn, Beatrice J. ScD Author Information

To the authors' knowledge, the incidence pelvic endometriosis in the general female population has not been previously reported. The purpose of the present study was to determine the incidence rate of diagnosed pelvic endometriosis among wh…

To test the widely accepted--but not well-supported--impression that endometriosis and infertility are associated, we compared the prevalence of endometriosis visualized at laparoscopy in 100 patients being evaluated for infertility and in …