Khosravifar M

No ORCID on file · 4 papers in corpus · active 2015-2026

Study types

  • rct 1

Condition tags

  • endometriosis 1
  • infertility 1
rct 2026
Administration of N-acetylcysteine influence the expression of apoptotic genes in the granulosa cells of infertile women diagnosed with endometriosis
Scientific reports ·doi:10.1038/s41598-025-34202-0

Endometriosis is a chronic, multifactorial disorder. Reactive oxygen species (ROS) and oxidative stress (OS) contribute to the development of endometriosis by affecting apoptosis-related genes in granulosa cells. N-acetylcysteine (NAC) is a…

2022
CYP19A1 Promoters Activity in Human Granulosa Cells: A Comparison between PCOS and Normal Subjects.
Cell journal ·doi:10.22074/cellj.2022.7787

ObjectiveEstrogen, a female hormone maintaining several critical functions in women's physiology, e.g., folliculogenesis and fertility, is predominantly produced by ovarian granulosa cells where aromatase enzyme converts androgen to estroge…

2022
TGFß Gene Members and Their Regulatory Factors in Granulosa Compared to Cumulus Cells in PCOS: A Case-Control Study.
Cell journal ·doi:10.22074/cellj.2022.8051

ObjectiveTransforming growth factor-beta (TGF-β) superfamily and its members that include bone morphogenetic protein 15 (BMP15), anti-Mullerian hormone (AMH), growth /differentiation factor-9 (GDF9), and their respective receptors: BMPR1A, …

2015
No relationship between most polymorphisms of steroidogenic acute regulatory (StAR) gene with polycystic ovarian syndrome.
International journal of reproductive biomedicine ·doi:10.29252/ijrm.13.12.771

BackgroundPolycystic ovary syndrome (PCOS) is one of the most common endocrine women's disorders in reproductive age. Hyperandrogenism has a critical role in the etiology of PCOS and it can cause fault in Steroidogenesis process. During ste…