Meirong Du

No ORCID on file · 9 papers in corpus · active 2021-2025

Study types

  • article 6
  • other 1
  • preprint 1
  • review 1

Condition tags

  • endometriosis 7
other 2025
Decreased CCL5 expression in endometrial stromal cells induces deficient CCR5 +CD4 + T cells in endometriosis
Acta biochimica et biophysica Sinica ·doi:10.3724/abbs.2024178

Endometriosis (EMS) is a benign gynecological disease characterized by the growth of endometrial tissue outside the uterine cavity. Evidence shows that the survival of patients with ectopic endometrial implants is associated with a dysregul…

article 2025
SCM-198 Inhibits EMS Development by Reversing Decreased Proportions of IFN-γ+T Cells and CCR5+T Cells
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-025-01823-9
article 2024
Cell membrane camouflaged and ROS responsive nanosomes for targeted endometriosis therapy via reversing inflammatory, low-autophagy, and immunotolerant microenvironment
·doi:10.1016/j.cej.2024.152697
article 2023
SCM-198 prevents endometriosis by reversing low autophagy of endometrial stromal cell via balancing ERα and PR signals
·doi:10.1016/j.jri.2023.103861
review 2023
The Critical Roles of Circular RNAs in Basic Research and Clinical Application of Female Reproductive-Related Diseases
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-022-01070-2

Circular RNAs (circRNAs), produced by precursor mRNAs, are a type of covalently closed circular molecule without 5' caps and 3' polyadenylated tails. Recently, advances in high-throughput sequencing, transcriptomics and bioinformatics, have…

article 2022
SCM-198 Alleviates Endometriosis by Suppressing Estrogen-ERα mediated Differentiation and Function of CD4+CD25+ Regulatory T Cells
International journal of biological sciences ·doi:10.7150/ijbs.68224

Background: Endometriosis (EMS), a typical endocrine immune disorder, associates with dramatically increased estrogen production and disorganized immune response in ectopic focus. Peritoneal regulatory T cells (Tregs) expansion in women wit…

preprint 2022
SCM-198 Prevents Endometriosis By Reversing Low Autophagy Levels Of Endometriotic Stromal Cells Via Inhibiting TNF-Α-Aromatase-Estrogen-Erα Pathway And Promoting PR Expression
·doi:10.21203/rs.3.rs-1228028/v1

Abstract Background: Endometriosis (EMS), an estrogen-dependent disease, is characterized by dysregulated inflammation and increased estrogen in ectopic lesions. However, the crosstalk and pathogenic mechanism of inflammation and estrogen h…

article 2022
SCM-198 Prevents Endometriosis by Reversing Low Autophagy of Endometrial Stromal Cell via Balancing ERα and PR Signals
Frontiers in endocrinology ·doi:10.3389/fendo.2022.858176

BACKGROUND: Endometriosis (EMS), an endocrine-related inflammatory disease, is characterized by estrogen and progesterone imbalance in ectopic lesions. However, its pathogenic mechanism has not been fully elucidated. While SCM-198 is the sy…

article 2021
TORC2/3-mediated DUSP1 upregulation is essential for human decidualization
Reproduction (Cambridge, England) ·doi:10.1530/rep-21-0036

Decidualization is the functional transformation process of endometrium in response to ovarian steroids dedicated to support embryo development. Defective decidualization is closely associated with various pregnancy complications such as re…