Endometriosis (EM) is a chronic estrogen-dependent gynecological disease that affects approximately 10% of women of reproductive age and is a leading cause of infertility worldwide. In addition to reproductive dysfunction, EM is associated …
ETHNOPHARMACOLOGICAL RELEVANCE: Ding-kun-dan (DKD), as one of well-known traditional Chinese medicine (TCM), is considered as an effective prescription to regulate menstruation, benefit Qi and nourish the blood. Previous studies had showed …
Objectives: Platinum-based chemotherapy as first-line treatment have shown promising results against tumors in thymic carcinoma (TC). However, clinical benefit has been limited to a small proportion of patients. We developed and validated …
Dysmenorrhea is the most common menstrual symptom among adolescent girls and young women. Most adolescents experiencing dysmenorrhea have primary dysmenorrhea. When the patient’s history suggests primary dysmenorrhea and will respond well t…
ObjectiveAdenomyosis is a common gynecologic disease. Alterations in the eutopic endometria might play an important role in the pathogenesis of adenomyosis. Long non-coding RNA (lncRNA) represents key regulators of gene expression. Our goal…
Adenomyosis is a prevalent gynecologic benign disease in women. Despite its significance, there is only a limited understanding of its pathological mechanisms. Talin1, a cytoskeletal protein, plays an important role in cell survival, prolif…
OBJECTIVE: To analyze the incidence of endometriosis in inpatients with infertility in Peking Union Medical College Hospital in 30 years. METHODS: The inpatients of Peking Union Medical College Hospital admitted between May 1983 and Novemb…
IntroductionEndometriosis is a chronic inflammatory condition. Interleukin (IL) 37 is a member of the IL-1 family and an anti-inflammatory cytokine. This study investigated the gene and protein expression of IL-37 in the eutopic and ectopic…