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ObjectiveTo evaluate a new levonorgestrel-releasing intrauterine system (LNG-IUS) called Levosert(®) for the treatment of heavy menstrual bleeding (HMB) in comparison to the reference product Mirena(®).MethodsA multicentre, randomised, cont…
BackgroundThis study was designed to develop an animal model to test the response of endometrium to local progestin delivery.MethodsProliferative human endometrium was subcutaneously grafted in two groups of SCID mice that received, 2 days …
ObjectiveTo evaluate, in a new original in vitro assay, putative factors that could modulate the adhesion of endometrial cells to peritoneum.DesignProspective, controlled in vitro study.SettingAcademic research laboratory.Patient(s)Fourteen…
ObjectiveTo investigate the role of different cellular types (epithelial and stromal endometrial cells and peritoneal cells) in the ectopic implantation of endometrium and to evaluate the importance of endocrine environment on the adhesion …