Nicola Pluchino

INTRODUCTION: Endometriosis is a chronic, oestrogen-dependent condition with a wide range of symptoms and comorbidities that significantly affect physical, emotional and psychological well-being, as well as quality of life. Women with endom…

Estrogens play an important role throughout a woman's life; therefore, disrupting their physiological production will alter hormonal balance with consequences for estrogen-related conditions, such as endometriosis and adenomyosis. The gut m…

ABSTRACT Background Endometriosis is associated with adverse pregnancy outcomes in standard observational studies, including placental complications, preterm birth, and caesarean delivery. However, causal inference from these studies is com…

STUDY QUESTION: Does IVF worsen pelvic pain in women with endometriosis? SUMMARY ANSWER: Nearly half of women with endometriosis reported perceived worsening of pelvic pain after IVF. WHAT IS KNOWN ALREADY: Prior studies generally suggest…

The management of endometriosis is influenced by numerous factors that extend beyond the biomedical realm. When it comes to issues such as therapeutic wandering, managing individual symptoms, and the influence of resources on access to care…

: Employment status is an independent predictor of HR-QoL in women with endometriosis. Beyond pain, professional identity and social integration play key roles in endometriosis burden.

The objective of this scoping review is to map the existing literature on digital patient decision aids (PtDAs) developed for women of reproductive age (18-49) with endometriosis, across a range of healthcare and digital health contexts.

BACKGROUND: Endometriosis is a chronic gynaecological condition affecting 2%-10% of women worldwide, often leading to severe pain, organ dysfunction and infertility. Despite its prevalence, diagnosis is frequently delayed, and treatment opt…

OBJECTIVES: The aim of the study was to evaluate current practices among gynecologists in managing large endometriomas before in vitro fertilization (IVF). DESIGN: A cross-sectional online survey was conducted. Participants/Materials: The …

OBJECTIVE: To study the use of intraoperative transvaginal ultrasound after bowel endometriosis shaving. DESIGN: Stepwise demonstration with a narrated video footage of preoperative and intraoperative ultrasound to evaluate the extent of a…

Gonadotrophin-releasing hormone (GnRH) antagonists have been demonstrated to reduce endometriosis-associated pain. Because of the hypo-oestrogenic state they induce, however, higher dosages of GnRH antagonists are not recommended for used l…

Uterine leiomyoma is the most common benign tumour of the uterus in women of reproductive age. When removed surgically, a mini-invasive procedure is preferentially used (laparoscopic or robotic) and the extraction of the specimen can be man…

Abstract Introduction Endometriosis impacts 1 in 10 women and can be a debilitating disease. Late diagnosis is a major challenge with Endometriosis, contributing further to the exacerbation of symptoms and suboptimal clinical management. Re…

OBJECTIVE: The aim of the present study is to conduct a qualitative investigation to provide a deeper understanding of women's views about endometriosis, fertility and their perception of reproductive options. METHODS: Semi-structured inter…

\nL’endométriose est une maladie chronique dans laquelle des lésions ressemblant à du tissu endométrial se retrouvent hors de l’utérus, principalement dans la cavité abdomino-pelvienne. Cette maladie pourrait toucher 10 % des femmes en âge …

L’endométriose est une maladie chronique dans laquelle des lésions ressemblant à du tissu endométrial se retrouvent hors de l’utérus, principalement dans la cavité abdomino-pelvienne. Cette maladie pourrait toucher 10 % des femmes en âge de…

Endometriosis is a chronic, multifactorial, estrogen-dependent disease. The abnormal endocrine microenvironment of endometriosis lesions is considered a main feature and multiple enzymatic pathways leading to local increased synthesis of es…

BACKGROUND: It is important to evaluate sequalae for complex chronic health conditions such as endometriosis and mental health disorders. Endometriosis impacts 1 in 10 women. Mental health outcomes can be a primary determinant in many physi…

PURPOSE: The purpose of this study was to investigate the impact of radiologist experience on diagnostic performance of pelvic magnetic resonance imaging (MRI) for the evaluation of endometriomas and different localisations of deep pelvic e…

Adult stem cells have a major role in endometrial physiology, including remodelling and repair. However, they also have a critical role in the development and progression of endometriosis. Bone marrow-derived stem cells engraft eutopic endo…

OBJECTIVE: To determine the relationship between steroid receptor expression and pain symptoms in endometriosis. DESIGN: Cross-sectional SETTING: University Hospital PATIENT(S): Women with endometriosis (N = 92). INTERVENTION(S): Tissue s…