Lukas Hefler

No ORCID on file · 6 papers in corpus
article 2013
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2013.03.029

ObjectiveEndometriotic spread to the lymphatic system has been described, but little is known about the molecular events and changes in gene expression associated with this process. We sought to determine the expression levels of a panel of…

article 2005
·doi:10.1097/01.gme.0000141760.98678.ed

OBJECTIVE: Genetic factors have been proposed as modulators of the timing of natural menopause. Single nucleotide polymorphisms (SNPs) of genes associated with thrombophilia and vascular homeostasis may interfere with ovarian function and t…

article 2005
Fertility and sterility ·doi:10.1016/j.fertnstert.2005.04.059

In the present nonrandomized pilot study we determined the role of the vaginally administered aromatase inhibitor anastrozole (0.25 mg anastrozole/d for 6 months) in the treatment of women with histologically proven rectovaginal endometrios…

article 2005
Obstetrics and gynecology ·doi:10.1097/01.aog.0000185259.01648.41

OBJECTIVE: Genetic as well as hormonal factors are known to influence the development and clinical course of endometriosis. We aimed to investigate the association among 10 single nucleotide polymorphisms (SNPs) involved in the estrogen met…

article 2003
Journal of the Society for Gynecologic Investigation ·doi:10.1016/s1071-5576(03)00006-6

ObjectiveExperimental data indicate that interleukin (IL)-1 plays a role in the pathogenesis of endometriosis. We determined the genotype and the allele frequencies of the IL1B exon 5 polymorphism and the corresponding IL-1beta serum levels…

article 1998
International journal of cancer ·doi:10.1002/(sici)1097-0215(19980821)79:4<434::aid-ijc21>3.0.co;2-3

The aim of the present study was to evaluate the clinical usefulness of the cytokeratin tumor marker M3/M21 as a screening marker for ovarian cancer, as a predictive marker in patients with adnexal masses and as a prognostic factor in women…