Chan HC
No ORCID on file
· 10 papers in corpus
· active 2001-2025
Study types
- article 3
- other 3
Condition tags
- endometriosis 6
- dysmenorrhea 1
- infertility 1
Top journals
Frequent coauthors
- Hsiao Chang Chan 6
- Hao Chen 6
- Wang C 5
- Tsang LL 4
- Cai Z 4
- Lai Ling Tsang 4
- Chaoqun Wang 4
- Jin A 3
- Aihong Jin 3
- Wen-Qing Huang 3
2025
BackgroundOvarian cancer is one of the top seven causes of cancer deaths. Incidence of ovarian cancer varies by ethnicity, where Asian women demonstrate lower incidence rates than non-Hispanic Blacks and Whites. Survival prediction models f…
other
2019
Rationale: Abnormal Wnt/β-catenin signaling in the endometrium can lead to both embryo implantation failure and severe pathogenic changes of the endometrium such as endometrial cancer and endometriosis. However, how Wnt/β-catenin signaling …
other
2018
Epithelial-to-mesenchymal transition (EMT) is postulated to be a prerequisite for the establishment of endometriosis (EMS), a common reproductive disorder in women. Our previous studies have demonstrated the elevated expression of transmemb…
2017
CD147 null mutant male mice are infertile with arrested spermatogenesis and increased apoptotic germ cells. Our previous studies have shown that CD147 prevents apoptosis in mouse spermatocytes but not spermatogonia. However, the underlying …
2017
Electronegative LDL-mediated cardiac electrical remodeling in a rat model of chronic kidney disease.
The mechanisms underlying chronic kidney disease (CKD)-associated higher risks for life-threatening ventricular tachyarrhythmias remain poorly understood. In rats subjected to unilateral nephrectomy (UNx), we examined cardiac electrophysiol…
2017
Multi-drug resistance protein 4 (MRP4), a potential chemotherapeutic target as well as a transporter for endogenous signaling molecules (e.g. prostaglandins), is known to be expressed in the endometrium, although its possible role(s) in the…
article
2017
// Wenqing Huang 1, 2, * , Aihong Jin 4, * , Jieting Zhang 1, 2 , Chaoqun Wang 1, 2 , Lai Ling Tsang 1, 2 , Zhiming Cai 4 , Xiaping Zhou 4 , Hao Chen 1, 2 and Hsiao Chang Chan 1, 2, 3 1 Epithelial Cell Biology Research Center, School of Bio…
article
2015
CONTEXT: Human endometriosis (EMS) is characterized by insufficient apoptosis. Our previous studies have shown elevated CD147 expression in human endometriotic tissues and its involvement in endometrial cell apoptosis. However, the exact un…
article
2014
ObjectiveTo examine the expression of CD147 in 60 human endometriosis lesions and how CD147 regulates migration and apoptosis in human uterine epithelial (HESs) cells.DesignExperimental clinical study and laboratory-based investigation.Sett…
other
2001
Apoptotic cell death of uterine epithelial cells is thought to play an important role in the onset of menstruation and the successful implantation of an embryo during early pregnancy. Abnormal apoptosis in these cells can result in dysmenor…