Xue-zhen Luo

No ORCID on file · 6 papers in corpus · active 2006-2017

Study types

  • article 6

Condition tags

  • mesh:D004715 6
  • endometriosis 6
article 2017
Synergistic effect of regulatory T cells and proinflammatory cytokines in angiogenesis in the endometriotic milieu
Human Reproduction ·doi:10.1093/humrep/dex067

STUDY QUESTION: Do regulatory T cells (Tregs) contribute to angiogenesis in endometriosis? SUMMARY ANSWER: High levels of CCL17 and CCL22 cause the recruitment of Tregs, upregulate the immunosuppression of Tregs and, in turn, may promote an…

article 2015
TLR4 Activation Promotes the Secretion of IL-8 Which Enhances the Invasion and Proliferation of Endometrial Stromal Cells in an Autocrine Manner via the FAK Signal Pathway
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/aji.12425

PROBLEM: Chronic inflammation is important for the occurrence of endometriosis, but the molecular mechanisms are still poorly understood. TLR4 is not only expressed on immune cells but is also present in the human endometrium, and its regul…

article 2012
CXCL8 enhances proliferation and growth and reduces apoptosis in endometrial stromal cells in an autocrine manner via a CXCR1-triggered PTEN/AKT signal pathway
Human Reproduction ·doi:10.1093/humrep/des132

BACKGROUND: Chemokine CXCL8 (also known as IL-8) has been identified as a potential regulator of endometrial stromal cells (ESCs), but it is unclear how CXCL8 regulates the survival of ESCs in the pathogenesis of endometriosis. METHODS: We …

article 2010
The high level of RANTES in the ectopic milieu recruits macrophages and induces their tolerance in progression of endometriosis
Journal of molecular endocrinology ·doi:10.1677/jme-09-0177

RANTES (C-C chemokine, regulated on activation, normal T cell expressed and secreted) is involved in progression of endometriosis, but the precise mechanism is understood inadequately. This study is to elucidate the roles of RANTES in macro…

article 2007
Combination of 17β-estradiol with the environmental pollutant TCDD is involved in pathogenesis of endometriosis via up-regulating the chemokine I-309–CCR8
Fertility and sterility ·doi:10.1016/j.fertnstert.2006.11.129
article 2006
Effects of combined 17β-estradiol with TCDD on secretion of chemokine IL-8 and expression of its receptor CXCR1 in endometriotic focus-associated cells in co-culture
Human Reproduction ·doi:10.1093/humrep/dei414

BACKGROUND: Chemokines play an important role in the pathogenesis of endometriosis. In the present study, the transcription of 18 chemokine receptors in eutopic endometrium and ectopic tissue with endometriosis was first analysed by RT-PCR.…