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BACKGROUND: Ovarian cancer is a gynecological malignancy associated with high mortality and poses significant clinical challenges in early diagnosis and precision treatment. Although the rapid advancement of artificial intelligence (AI) has…

BackgroundPolycystic ovary syndrome (PCOS) is associated with a significantly high risk of spontaneous abortion, yet there is a scarcity of clinical prediction models for early pregnancy loss in this patient population.ObjectiveTo identify …

BACKGROUND: Gallbladder cancer (GBC) is a highly aggressive malignancy with an extremely poor prognosis, and its high postoperative recurrence rate is a major challenge affecting long-term patient survival. Accurately predicting individuali…

Uterine leiomyoma is a common benign tumor of the uterus and typically demonstrates low FDG uptake on 18F-FDG PET/CT. Intense FDG uptake in a uterine mass is generally considered suggestive of malignancy. Here, we report a case of uterine l…

BACKGROUND: Endometrial receptivity (ER) is critical for embryo implantation, and its impairment is a major contributor to infertility. Current ER evaluation methods are invasive and poorly standardized. Shear wave elastography (SWE) offers…

Abdominal wall endometriosis is rare. Malignant transformation of abdominal wall endometriosis is extremely rare. We describe FDG PET/CT findings in a case of clear cell carcinoma arising from abdominal wall endometriosis with multiple lymp…

This study explored the genetic evidence linking triglyceride-related pathways and lipid-lowering drug targets with endometriosis risk and investigated the genetic association between TG levels and EM. Using genome-wide association study (G…

Cytoreductive surgery is the treatment protocol for colorectal cancer. Nonetheless, a major medical challenge remains to fully eliminate malignant tumor cells, along with a number of complications such as peritoneal adhesion and tumor perit…

OBJECTIVE: To evaluate the efficacy and safety of LED red light therapy in alleviating primary dysmenorrhea. METHODS: A total of 119 patients with primary dysmenorrhea were enrolled in 2022. The intervention was LED red light therapy admin…

BACKGROUND: Optimal endometrial thickness and receptivity, precisely regulated by steroid hormones, are critical determinants for successful embryo implantation. Thin endometrium is a major cause of female infertility, yet its pathogenesis …

Transvaginal ultrasound-guided oocyte retrieval is routine for assisted reproduction, but unfit for some special patients. We report an elderly infertile patient with adenomyosis, whose transvaginal retrieval was high risk. Intraoperative c…

BACKGROUND: Elevated homocysteine (HCY) and hyperandrogenism are key metabolic disturbances in polycystic ovary syndrome (PCOS), but their relationship across different reproductive outcomes remains unclear. OBJECTIVE: To investigate outco…

BACKGROUND: Numerous studies have suggested that assessing endometrial and subendometrial blood flow can contribute to the evaluation of endometrial receptivity. However, there remains a lack of unified expert consensus regarding the assess…

Adenomyosis is a common gynecological disorder with incompletely understood pathogenesis. Through single-cell RNA sequencing of adenomyosis tissues, we identified epithelial-endothelial transition (EET) as a key pathological mechanism and d…

Cannabidiol (CBD), a non-psychoactive and non-addictive phytocannabinoid derived from Cannabis sativa L., has attracted increasing attention for its therapeutic potential in intestinal diseases. Accumulating evidence indicates that CBD exer…

Fibrosis is a defining feature of endometriosis (EMS). Our previous single-cell RNA sequencing (scRNA-seq) revealed myofibroblasts (MFBs) as the predominant cells in ectopic endometrium (ECE), mainly derived from fibroblast-to-myofibroblast…

BACKGROUND: Cervical pregnancy (CP) is a rare but life-threatening ectopic gestation with high risk of catastrophic hemorrhage during evacuation. Uterine artery embolization (UAE) combined with dilation and curettage (D&C) has been proposed…

BACKGROUND: Endometriosis is a chronic inflammatory disorder affecting ~ 10% of reproductive-age women, often causing pelvic pain and infertility. Despite its prevalence, diagnosis remains delayed due to non-specific symptoms and lack of re…

BACKGROUND: No prognostic evaluation criteria have been established for either human papillomavirus (HPV)-related cervical adenocarcinoma (HPV-CA) or HPV-independent cervical adenocarcinoma (HPV-Ind-CA). We aimed to compare and analyze the …

This study investigates the effects of astaxanthin on oxidative stress, mitochondrial function, and follicular development in mouse preantral follicles, with a focus on the involvement of the adenosine monophosphate-activated protein kinase…

Adding plant extracts to diets to enhance sow performance and health is widely regarded as a healthy and sustainable practice. In promoting antibiotic-free farming, plant extracts have emerged as a leading solution for enhancing sow fertili…

RATIONALE: The incidence of intra-abdominal hernia is very low, ranging from 0.2% to 0.9% in autopsy cases and 0.5% to 4.1% in cases of intestinal obstruction. Broad ligament hernia accounts for 4% to 7% of all cases of intra-abdominal hern…

Uterine artery embolization (UAE) is an effective treatment for adenomyosis, but ovarian collateral supply can increase the risk of recurrence. This study aimed to explore the safety and efficacy of combined UAE and unilateral ovarian arter…

BackgroundEndoscopic gallbladder-preserving cholecystolithotomy (EGPC) has become an alternative option for treating cholecystolithiasis. However, developing a new method of EGPC in which the gallbladder wall is not damaged remains a challe…

Cancer remains a critical global health challenge, driven by tumor angiogenesis and immune evasion. Endostatin, a collagen XVIII-derived fragment, uniquely suppresses angiogenesis and reprograms the immunosuppressive tumor microenvironment …