Che X

No ORCID on file · 8 papers in corpus · active 2014-2024

Study types

  • article 5
  • preprint 1
  • rct 1

Condition tags

  • endometriosis 4
  • adenomyosis 4
  • dysmenorrhea 2
preprint 2024
Exosomal MiR-92a-3p serves as a Promising Diagnostic Marker and Potential Therapeutic Target for Adenomyosis
·doi:10.21203/rs.3.rs-3961335/v1

Abstract This study aimed to elucidate the role of microRNA miR-92a-3p in the pathogenesis of adenomyosis. We focused on understanding how miR-92a-3p in exosomes derived from ectopic lesions influences the behavior of endometrial cells, DR…

2024
Expression and clinical significance of miR-141-5p as a biomarker in the serum of patients with early spontaneous abortion.
Clinics (Sao Paulo, Brazil) ·doi:10.1016/j.clinsp.2024.100327

AimmiR-141-5p expression in patients with Early Spontaneous Abortion (ESA) and its correlation with hormone levels during pregnancy were investigated.MethodsA total of 70 pregnant women with ESA were selected as the research group, and 70 n…

article 2024
Immunomodulation in Endometriosis: Investigating the interrelationship between VISTA expression and Escherichia.Shigella-Associated metabolites
International immunopharmacology ·doi:10.1016/j.intimp.2024.112366

AIMS: Endometriosis is characterized by an abnormal immune microenvironment. Despite the extensive use of immune therapies, the application of immune checkpoint inhibitors in endometriosis lacks confidence due to the instability of preclini…

rct 2023
Effect of Mifepristone vs Placebo for Treatment of Adenomyosis With Pain Symptoms: A Randomized Clinical Trial
JAMA network open ·doi:10.1001/jamanetworkopen.2023.17860

IMPORTANCE: Adenomyosis is a common chronic gynecological disorder, and its treatment is an unmet need. New therapies need to be developed. Mifepristone is being tested for adenomyosis treatment. OBJECTIVE: To determine whether mifepriston…

article 2021
Recepteur d'origine nantais contributes to the development of endometriosis via promoting epithelial‐mesenchymal transition of a endometrial epithelial cells
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.16261

Endometriosis is a benign, chronic inflammatory disease that commonly occurs in reproductive-aged women. Epithelial-mesenchymal transition (EMT) of endometrial epithelial cells plays an important role in the development of endometriosis. Re…

article 2020
The new application of mifepristone in the relief of adenomyosis-caused dysmenorrhea
International journal of medical sciences ·doi:10.7150/ijms.39252

Background: Adenomyosis is a quite common gynecological disorder and above 30% of patients have typical secondary and progressive dysmenorrhea. Current treatments still have many disadvantages and thereby the novel treatment aiming to relie…

article 2019
A new trick for an old dog: The application of mifepristone in the treatment of adenomyosis
Journal of cellular and molecular medicine ·doi:10.1111/jcmm.14866

Adenomyosis is also called internal endometriosis and affects about 20% of reproductive-aged women. It seriously reduces life quality of patients because current drug therapies face with numerous challenges. Long-term clinical application o…

article 2014
Is nerve-sparing surgery suitable for deeply infiltrating endometriosis?
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2014.01.027

ObjectiveTo investigate the efficacy of nerve-sparing surgery for deeply infiltrating endometriosis (DIE) and the bladder and sexual dysfunction that follow this procedure.Study designA total of 108 women with DIE underwent conventional sur…