W B Nothnick

No ORCID on file · 8 papers in corpus · active 1994-2010

Study types

  • article 5
  • other 2
  • review 1

Condition tags

  • mesh:D004715 7
  • endometriosis 7
  • infertility 1
article 2010
Endometriosis: in search of optimal treatment.
Minerva ginecologica

Endometriosis is an enigmatic, debilitating disease which affects as many as 15% of all women of reproductive age and is characterized by pelvic pain and infertility. Current treatment regimes used to manage the disease do so by inducing a …

article 2001
CD44s Expression is Reduced in Endometriotic Lesions Compared to Eutopic Endometrium in Women with Endometriosis
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists ·doi:10.1097/00004347-200104000-00005

Immunohistochemical expression of the standard form of CD44 (CD44s) was examined in archival formalin-fixed endometriotic and matching eutopic endometrial tissue obtained from 25 patients in proliferative (N = 16) and secretory (N = 9) stag…

review 2001
Treating endometriosis as an autoimmune disease
Fertility and Sterility ·doi:10.1016/s0015-0282(01)01878-7
article 1998
Gonadotropin-Releasing Hormone Agonist (GnRH-a) Therapy Alters Activity of Plasminogen Activators, Matrix Metalloproteinases, and Their Inhibitors in Rat Models for Adhesion Formation and Endometriosis: Potential GnRH-a–Regulated Mechanisms Reducing Adhesion Formation
Fertility and Sterility ·doi:10.1016/s0015-0282(98)00032-6
article 1998
Novel Implications in the Development of Endometriosis: Biphasic Effect of Macrophage Activation on Peritoneal Tissue Expression of Tissue Inhibitor of Metalloproteinase‐1
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1998.tb00067.x

PROBLEM: Elevated levels of activated macrophages are associated with endometriosis, but their role in the etiology of the disease is uncertain. The current study was undertaken to examine whether activated macrophages could modulate perito…

article 1996
Divergent effects of interleukin-1 beta on steroidogenesis and matrix metalloproteinase inhibitor expression and activity in cultured rat granulosa cells
·doi:10.1210/en.137.9.3784

The periovulatory increase in ovarian matrix metalloproteinase inhibitor (MMPI) expression is regulated both in vitro and in vivo by LH, but the intermediary steps in this process are uncertain. The purpose of this experiment was to determi…

other 1994
Detection of a unique 32-kd protein in the peritoneal fluid of women with endometriosis
Fertility and Sterility ·doi:10.1016/s0015-0282(16)56519-4

OBJECTIVE: To test the hypothesis that endometriotic tissue secretes endometriotic-specific proteins into the peritoneal fluid (PF) of women with endometriosis. DESIGN: A prospective design was utilized in this study. SETTING: Tertiary ca…

other 1994
Immunomodulation of rat endometriotic implant growth and protein production
American journal of reproductive immunology (New York, N.Y. : 1989) ·doi:10.1111/j.1600-0897.1994.tb00860.x

PROBLEM: The immune system has been implicated in the pathophysiology of endometriosis. To determine if modulation of the immune system influences endometriotic implant growth and protein production, the following experiment was conducted. …