The matrix metalloproteinases (MMPs) are postulated to facilitate ovulation by remodeling the follicular wall. The MMP family is comprised of 25 different proteinases, many of which share common structural and functional characteristics and…
Alterations in the interaction between the follicle and the matrix must occur before follicular rupture and ovulation can take place. Such interactions are controlled in part by the delicate balance between the matrix metalloproteinases (MM…
In the ovary, the matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases (TIMPs) have been postulated to play a critical role in extracellular matrix remodeling associated with ovulation as well as luteal formation…
ObjectiveTo characterize the expression of basigin in ovarian endometriotic tissue, normal ovary, and endometrium during the menstrual cycle.DesignControlled, retrospective study for evaluation of basigin expression in archived specimens.Se…
ObjectiveTo evaluate the effects of a gonadotropin-releasing hormone agonist (GnRH-a) on plasminogen activator (PA), matrix metalloproteinase (MMP), plasminogen activator inhibitor (PAI) and matrix metalloproteinase inhibitor (MMPI) activit…
ObjectiveOur purpose was to determine in the rat model whether endometriosis could influence ovarian function by altering oocyte release or folliculogenesis.Study designWe histologically examined the ovaries of reproductively cycling rats w…
The influence of ovarian adrenergic nerves on follicular growth during the estrous cycle in the adult guinea pig was ascertained by comparing follicular development in control and chemically sympathectomized ovaries from the same animal. Se…
The structure of the human ovarian ligament was studied with light and electron microscopy, with emphasis on neural components. The ligament is primarily composed of smooth muscle arranged in an outer oblique and an inner longitudinal layer…