Ioana Păvăleanu

Adenomyosis and endometriosis are chronic, estrogen-dependent gynecological disorders traditionally regarded as distinct entities but increasingly recognized as interrelated conditions within a shared disease spectrum. Both are characterize…

The perception that hormonal contraception causes weight gain is a general belief that frequently hinders the initiation and continuation of effective family planning. This narrative review analyses data from Cochrane systematic reviews and…

Adenomyosis is a benign uterine disorder characterized by the infiltration of endometrial tissue into the myometrium, often associated with debilitating symptoms such as heavy menstrual bleeding, severe pelvic pain and infertility. Traditio…

The link between endometriosis and ovarian carcinoma has been recognized early on, initially termed endometriosis-associated ovarian carcinoma and subsequently referred to as endometriosis-associated ovarian carcinoma (EAOC). The relationsh…

Aim: Endometriosis, a chronic estrogen-dependent disease, is associated with persistent pelvic pain and is classified as a neuro-inflammatory disorder.This study aimed to decipher the inflammatory milieu in endometriosis, focusing on the ly…

Atypical polypoid adenomyoma (APAM) is a rare polypoid benign tumor of the uterus that causes irregular vaginal bleeding in women of reproductive age. It has the potential for malignant transformation, but it does not metastasize. APAM may …

Endometriosis represents an estrogen-dependent disease of the female reproductive system and intra- and extraperitoneal regions, with chronic feature. Currently, immune cells, such as macrophages and lymphocytes, are considered to play a pi…

BMI-1 is a key component of stem cells, which are essential for normal organ development and cell phenotype maintenance. BMI-1 expression is deregulated in cancer, resulting in the alteration of chromatin and gene transcription repression. …

BACKGROUND: Endometriosis is a benign estrogen-dependent gynecological disease involving components of the female genital tract (uterus, Fallopian tubes, ovaries, large, round, and utero-sacral ligaments) and intra- and extraperitoneal regi…

Firstly described at the end of nineteenth century, endometriosis remains an enigmatic disease, from etio-pathogenesis to specific markers of diagnosis and its ability to associate with malignancies. Our review has been designed from a hist…

Objective: Endometriosis association with cancers is strongly supported by epidemiological criteria and shared protective factors, being identified as endometriosis-associated ovarian carcinoma (EOC). In this context, our study objective ha…

Abdominal wall endometriosis (AWE) is a rare condition defined by the presence of endometrial tissue in the subcutaneous fatty layer and the muscles of the abdominal wall. It is usually caused by the dissemination of endometrial tissue in t…

INTRODUCTION: Endometriosis is a disease that affects 7-10% of reproductive-age women. When its diagnosis is delayed, its management becomes more difficult. Both for earlier detection and for therapeutic follow-up, discovering noninvasive b…

Endometriosis represents a complex entity, characterized by tissue located in ectopic sites, outside uterus, with the highest incidence in ovaries and peritoneum. We report a rare case, with multiple endometriotic foci, in a 34 year old wom…