Roden R

No ORCID on file · 4 papers in corpus · active 2008-2013
2013
Evaluation of DNA from the Papanicolaou test to detect ovarian and endometrial cancers.
Science translational medicine ·doi:10.1126/scitranslmed.3004952

Papanicolaou (Pap) smears have revolutionized the management of patients with cervical cancers by permitting the detection of early, surgically curable tumors and their precursors. In recent years, the traditional Pap smear has been replace…

2010
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinoma.
Science (New York, N.Y.) ·doi:10.1126/science.1196333

Ovarian clear cell carcinoma (OCCC) is an aggressive human cancer that is generally resistant to therapy. To explore the genetic origin of OCCC, we determined the exomic sequences of eight tumors after immunoaffinity purification of cancer …

2008
Antigen-specific immunotherapy of cervical and ovarian cancer.
Immunological reviews ·doi:10.1111/j.1600-065x.2008.00622.x

We contrast the efforts to treat ovarian cancer and cervical cancer through vaccination because of their different pathobiology. A plethora of approaches have been developed for therapeutic vaccination against cancer, many of which target d…

2008
Early detection and treatment of ovarian cancer: shifting from early stage to minimal volume of disease based on a new model of carcinogenesis.
American journal of obstetrics and gynecology ·doi:10.1016/j.ajog.2008.01.005

The goal of ovarian cancer screening is to detect disease when confined to the ovary (stage I) and thereby prolong survival. We believe this is an elusive goal because most ovarian cancer, at its earliest recognizable stage, is probably not…