Kirma NB

No ORCID on file · 7 papers in corpus · active 2009-2021

Study types

  • article 6
  • preprint 1

Condition tags

  • endometriosis 6
  • infertility 1
article 2021
Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium
Molecular and cellular endocrinology ·doi:10.1016/j.mce.2021.111481

Endometriosis is a debilitating gynecologic disorder that affects ∼10% of women of reproductive age. Endometriosis is characterized by growth of endometriosis lesions within the abdominal cavity, generally thought to arise from retrograde m…

preprint 2021
Endometrial Gap Junction Expression - Early Indicators of Endometriosis and Integral to Invasiveness
·doi:10.1101/2021.01.25.428135

Abstract Endometriosis is an invasive disease, and a leading cause of pain, infertility and disability among women, with an incidence 10 fold that of cancer. A more complete understanding of disease pathogenesis is essential for the develop…

article 2012
Increased expression of macrophage colony–stimulating factor and its receptor in patients with endometriosis
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.02.007

ObjectiveTo investigate the expression and regulation of colony-stimulating factor 1 (CSF-1) and its receptor, C-FMS, in endometriosis.DesignIn vivo and vitro study.SettingUniversity-based academic medical center.Patient(s)Reproductive-age …

article 2012
Raf-1, a Potential Therapeutic Target, Mediates Early Steps in Endometriosis Lesion Development by Endometrial Epithelial and Stromal Cells
Endocrinology ·doi:10.1210/en.2011-1879

Endometriosis is a hormone-sensitive gynecological disorder characterized by the benign growth of endometrial-like tissue in the pelvic cavity. Endometriotic lesions composed of endometrial stromal cells (ESC) and glandular epithelial cells…

article 2011
Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.03.026

Although macrophage colony-stimulating factor (CSF-1) has been suggested to play a role in maintaining the chronic inflammatory response in endometriosis, our data suggest that CSF-1 may also play a role in early endometriosis lesion format…

article 2010
Imatinib decreases endometrial stromal cell transmesothial migration and proliferation in the extracellular matrix of modeled peritoneum
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.04.018

ObjectiveTo characterize imatinib's effect on endometrial stromal cell (ESC) attachment, proliferation, and invasion in modeled peritoneum.DesignIn vitro study.SettingAcademic medical center.Patient(s)Twelve normally cycling women.Intervent…

article 2009
Induction of endometrial epithelial cell invasion and c-fms expression by transforming growth factor beta
Molecular human reproduction ·doi:10.1093/molehr/gap043

Transforming growth factor beta 1 (TGF-beta1) levels are increased in the peritoneal fluid of endometriosis patients, and endometrial cells express TGF-beta signaling components; however, little is known regarding the role of TGF-beta in en…