Tessier-Cloutier B

No ORCID on file · 9 papers in corpus · active 2017-2026

Study types

  • article 5
  • preprint 2
  • other 1

Condition tags

  • endometriosis 7
  • die_deep_infiltrating 2
  • infertility 1
article 2026
The Role of Molecular Characterization in Precision Medicine in Endometriosis
Obstetrics and gynecology ·doi:10.1097/aog.0000000000006352

Endometriosis is a chronic condition in which tissue similar to the lining of the uterus grows in other parts of the body. It affects roughly 1 in 10 women of reproductive age, often causing severe pelvic pain and infertility. Despite how c…

article 2022
Molecular analysis suggests oligoclonality and metastasis of endometriosis lesions across anatomically defined subtypes
Fertility and sterility ·doi:10.1016/j.fertnstert.2022.05.030

OBJECTIVE: To investigate the heterogeneity of somatic cancer-driver mutations within patients and across endometriosis types. DESIGN: A single-center cohort, retrospective study. SETTING: Tertiary specialist-care center at a university h…

preprint 2021
Molecular analysis suggests oligoclonality and metastasis of endometriosis lesions across anatomically defined subtypes
·doi:10.1101/2021.04.12.21255355

Abstract Endometriosis symptoms are heterogeneous with controversy on whether it constitutes a single disease or multiple distinct types. Our previous work found recurrent somatic cancer-driver alterations in endometriosis; however, these h…

2020
Napsin-A and AMACR are Superior to HNF-1β in Distinguishing Between Mesonephric Carcinomas and Clear Cell Carcinomas of the Gynecologic Tract.
Applied immunohistochemistry & molecular morphology : AIMM ·doi:10.1097/pai.0000000000000801

Mesonephric carcinoma is a rare gynecologic neoplasm commonly mistaken for clear cell carcinoma, because of their overlapping morphologic features. Both tumors are negative for estrogen receptor and p16, magnifying this diagnostic dilemma. …

preprint 2019
Oncogenic Mutations in Histologically Normal Endometrium: The New Normal?
·doi:10.1101/561050

Abstract The presence of somatic driver mutations in endometriosis has previously been believed to represent early events in transformation, however our group and others have described such mutations in roughly one-third of cases of deep in…

article 2018
Iatrogenic endometriosis harbors somatic cancer-driver mutations
Human Reproduction ·doi:10.1093/humrep/dey332

STUDY QUESTION: Does incisional endometriosis (IE) harbor somatic cancer-driver mutations? SUMMARY ANSWER: We found that approximately one-quarter of IE cases harbor somatic-cancer mutations, which commonly affect components of the MAPK/RAS…

article 2017
Cancer-Associated Mutations in Endometriosis without Cancer
The New England journal of medicine ·doi:10.1056/nejmoa1614814

BACKGROUND: Endometriosis, defined as the presence of ectopic endometrial stroma and epithelium, affects approximately 10% of reproductive-age women and can cause pelvic pain and infertility. Endometriotic lesions are considered to be benig…

other 2017
Clear cell and endometrioid carcinomas: are their differences attributable to distinct cells of origin?
The Journal of Pathology ·doi:10.1002/path.4934

Endometrial epithelium is the presumed tissue of origin for both eutopic and endometriosis-derived clear cell and endometrioid carcinomas. We had previously hypothesized that the morphological, biological and clinical differences between th…

article 2017
LINE-1 retrotransposon-mediated DNA transductions in endometriosis associated ovarian cancers
Gynecologic oncology ·doi:10.1016/j.ygyno.2017.09.032

ObjectiveEndometrioid (ENOC) and clear cell ovarian carcinoma (CCOC) share a common precursor lesion, endometriosis, hence the designation endometriosis associated ovarian cancers (EAOC). Long interspersed nuclear element 1 (LINE-1 or L1), …