Najafi T

No ORCID on file · 4 papers in corpus · active 2011-2017

Condition tags

  • infertility 1
2017
Cyclophosphamide and acrolein induced oxidative stress leading to deterioration of metaphase II mouse oocyte quality.
Free radical biology & medicine ·doi:10.1016/j.freeradbiomed.2017.05.006

Cyclophosphamide (CTX) is a chemotherapeutic agent widely used to treat ovarian, breast, and hematological cancers as well as autoimmune disorders. Such chemotherapy is associated with reproductive failure and premature ovarian insufficienc…

2015
Diffused Intra-Oocyte Hydrogen Peroxide Activates Myeloperoxidase and Deteriorates Oocyte Quality.
PloS one ·doi:10.1371/journal.pone.0132388

Hydrogen peroxide (H2O2) is a relatively long-lived signaling molecule that plays an essential role in oocyte maturation, implantation, as well as early embryonic development. Exposure to relatively high levels of H2O2 functions efficiently…

2012
Altered endometrial expression of endothelial nitric oxide synthase in women with unexplained recurrent miscarriage and infertility.
Reproductive BioMedicine Online ·doi:10.1016/j.rbmo.2012.07.004

Endothelial nitric oxide synthase (eNOS) has diverse roles in the female reproductive system including a role in blastocyst implantation. Aberrant expression of eNOS could therefore be significant in the pathogenesis of disorders of implant…

2011
Increase in concentration of soluble HLA-G in high-quality embryos after intracytoplasmic sperm injection.
Anatomy & cell biology ·doi:10.5115/acb.2011.44.4.331

Non-invasive methods are normally preferred to conventional invasive methods when selecting suitable embryos to improve pregnancy rates after assisted reproduction techniques. One of the most recognized non-invasive methods is to examine th…