I M Spitz

No ORCID on file · 7 papers in corpus · active 1996-2010

Study types

  • review 3
  • article 2
  • book-chapter 1
  • case-report 1

Condition tags

  • endometriosis 6
  • adenomyosis 1
book-chapter 2010
·doi:10.5005/jp/books/11032_27
article 2003
Human Reproduction ·doi:10.1093/humrep/deg179

BACKGROUND: The levonorgestrel-releasing intra-uterine system (LNg-IUS) has been used to control menorrhagia, but irregular bleeding during the first 3 months of use was the most notable side effect. Endometrial angiogenesis is believed to …

article 2001
Human Reproduction ·doi:10.1093/humrep/16.10.2103

BACKGROUND: The levonorgestrel-releasing intrauterine system (LNg-IUS) has been shown to be effective in the management of menorrhagia. In order to evaluate the effects of LNg-IUS on endometrial proliferation and apoptosis, proliferating ce…

case-report 2001
Clinical endocrinology ·doi:10.1046/j.1365-2265.2001.01026.x

Mifepristone (RU486) is a potent antiprogestagen, and at high doses it also acts as an antiglucocorticoid drug. Mifepristone, administered as a single 600 mg dose, is commonly employed to induce medical abortion in conjunction with prostagl…

review 2000
Steroids ·doi:10.1016/s0039-128x(00)00194-x
review 1998
Human reproduction update ·doi:10.1093/humupd/4.5.584

Considerable progress has been made in elucidating the mechanism of action of antiprogestins. The biological response to a progesterone antagonist depends on many factors. The usual effect is that of an antagonist, but progesterone agnostic…

review 1996
Annual review of pharmacology and toxicology ·doi:10.1146/annurev.pa.36.040196.000403

Antiprogestins are characterized by substitutions at the 11 beta and 17 alpha positions of the steroid ring system and bind strongly to both progesterone and glucocorticoid receptors. Although they function predominantly as antiprogestins a…