Shuhui Hou

No ORCID on file · 7 papers in corpus · active 2020-2024

Study types

  • article 5
  • other 1
  • preprint 1

Condition tags

  • endometriosis 7
  • endometrioma 2
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
  • infertility 1
other 2024
Overexpressed nicotinamide N‑methyltransferase in endometrial stromal cells induced by macrophages and estradiol contributes to cell proliferation in endometriosis
Cell death discovery ·doi:10.1038/s41420-024-02229-3

Endometriosis, an estrogen-dependent chronic inflammatory condition, afflicts reproductive-aged women. However, the underlying pathological mechanisms remain to be elucidated. Nicotinamide N-methyltransferase (NNMT) is a critical enzyme inv…

article 2022
Downregulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of signal transducer and activator of transcription 1 in endometriosis
Biology of reproduction ·doi:10.1093/biolre/ioac081

BACKGROUND: Endometriosis is a benign gynecologic disease that causes chronic pelvic pain, dysmenorrhea and infertility and shares several characteristics with malignant tumors, afflicting women of reproductive age. Hexokinase 2 plays an es…

article 2022
Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16- NK-cell differentiation
Experimental & molecular medicine ·doi:10.1038/s12276-022-00793-1

Prostacyclin (PGI2) plays key roles in shaping the immune microenvironment and modulating vasodilation, whereas its contribution to endometriosis (EMs) remains largely unclear. Our study suggested that prostacyclin synthase (PTGIS)-dependen…

article 2022
PrPC Promotes Endometriosis Progression by Reprogramming Cholesterol Metabolism and Estrogen Biosynthesis of Endometrial Stromal Cells through PPARα Pathway
International journal of biological sciences ·doi:10.7150/ijbs.68015

Endometriosis (EMs) is characterized as an estrogen-dependent disease. Whereas, the underlying mechanism for activated estrogen biosynthesis in EMs lesions is largely unknown. We analyzed cholesterol metabolism and estrogen biosynthesis con…

preprint 2021
Down-Regulating Hexokinase 2 Inhibits Proliferation of Endometrial Stromal Cells Through a Noncanonical Pathway Involving Phosphorylated-STAT1 in Endometriosis
·doi:10.21203/rs.3.rs-845266/v1
article 2021
Follistatin-like I promotes endometriosis by increasing proinflammatory factors and promoting angiogenesis
Reproduction (Cambridge, England) ·doi:10.1530/rep-21-0094

Endometriosis (EMS) is a chronic benign inflammatory disease characterized by the growth of endometrial-like tissue in aberrant locations outside of the uterine cavity. Angiogenesis and abnormal immune responses are the fundamental requirem…

article 2020
Estrogen-regulated CD200 inhibits macrophage phagocytosis in endometriosis
Journal of reproductive immunology ·doi:10.1016/j.jri.2020.103090