Tu Z

No ORCID on file · 7 papers in corpus · active 2015-2025

Study types

  • article 1

Condition tags

  • endometriosis 1
2025
Scientific reports ·doi:10.1038/s41598-025-14390-5

Uterine fibroids are common among women of reproductive age and often recur after treatment. Accurate recurrence prediction is essential for guiding clinical decisions, yet existing models remain inadequate. This study aimed to develop a no…

2025
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.2504361122

Progesterone receptor (PR)-mediated progesterone (P4) signaling plays a crucial role in the establishment of uterine receptivity which is the prerequisite for successful embryo implantation in mammals. However, detailed molecular mechanisms…

article 2024
Frontiers in endocrinology ·doi:10.3389/fendo.2024.1397670

OBJECTIVE: To investigate the causal effect of immune cells on endometriosis (EMS), we performed a Mendelian randomization analysis. METHODS: Mendelian randomization (MR) uses genetic variants as instrumental variables to investigate the c…

2024
Nature communications ·doi:10.1038/s41467-024-49930-6

Abnormal trophoblast self-renewal and differentiation during early gestation is the major cause of miscarriage, yet the underlying regulatory mechanisms remain elusive. Here, we show that trophoblast specific deletion of Kat8, a MYST family…

2023
Frontiers in endocrinology ·doi:10.3389/fendo.2023.1229862

Embryo implantation and placentation play pivotal roles in pregnancy by facilitating crucial maternal-fetal interactions. These dynamic processes involve significant alterations in gene expression profiles within the endometrium and trophob…

2016
Journal of hematology & oncology ·doi:10.1186/s13045-016-0236-7

Cancer is currently one of the leading causes of death worldwide and is one of the most challenging major public health problems. The main challenges faced by clinicians in the management and treatment of cancer mainly arise from difficulti…

2015
Scientific reports ·doi:10.1038/srep13735

Human endometrium decidualization, which involves endometrial stromal proliferation and differentiation, is a prerequisite for embryo implantation, thus successful pregnancy. The Forkhead Box M1 (FoxM1), previously known as HNF-3, HFH-11, M…