Noske A

No ORCID on file · 8 papers in corpus · active 2008-2024

Study types

  • other 3
  • article 2
  • review 1

Condition tags

  • endometriosis 6
  • adenomyosis 1
other 2024
Expression patterns of HDAC6 in correlation to ARID1A status in different subtypes of endometriosis: A retrospective tissue microarray analysis
European journal of obstetrics, gynecology, and reproductive biology ·doi:10.1016/j.ejogrb.2024.08.044

Endometriosis is a disease affecting approximately 10% of reproductive age women. Loss of the tumor suppressor gene AT-rich interactive domain-containing protein 1A (ARID1A) occurs in some endometriosis cases. Histone deacetylase 6 (HDAC-6)…

other 2023
The immunohistochemical expression of GPER and classical sex hormone receptors differs in adenomyosis and eutopic endometrium
Journal of reproductive immunology ·doi:10.1016/j.jri.2023.103795

G protein-coupled estrogen receptor (GPER) has been found to be an important key regulator in the homeostasis of sex hormone-dependent human cells. The aim of this study was to compare the expression of GPER, estrogen receptor alpha (ER-α),…

2017
Tracking the origin of simultaneous endometrial and ovarian cancer by next-generation sequencing - a case report.
BMC cancer ·doi:10.1186/s12885-017-3054-6

BackgroundEndometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer …

review 2013
ARID1A mutations and PI3K/AKT pathway alterations in endometriosis and endometriosis-associated ovarian carcinomas
International journal of molecular sciences ·doi:10.3390/ijms140918824

Endometriosis is a common gynecological disease affecting 6%-10% of women of reproductive age and is characterized by the presence of endometrial-like tissue in localizations outside of the uterine cavity as, e.g., endometriotic ovarian cys…

other 2013
The expression of histone deacetylase 1, but not other class I histone deacetylases, is significantly increased in endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719113488450

Class I histone deacetylases (HDACs-1-3) play an important role in steroid hormone-dependent gene expression and in modulating cell survival and proliferation. We analyzed their expression in a tissue microarray including 74 endometriosis s…

article 2012
Expression of the G protein-coupled estrogen receptor (GPER) in endometriosis: a tissue microarray study
Reproductive biology and endocrinology : RB&E ·doi:10.1186/1477-7827-10-30

BACKGROUND: The G protein-coupled estrogen receptor (GPER) is thought to be involved in non-genomic estrogen responses as well as processes such as cell proliferation and migration. In this study, we analyzed GPER expression patterns from e…

article 2012
Loss of ARID1A/BAF250a-expression in endometriosis: a biomarker for risk of carcinogenic transformation?
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc ·doi:10.1038/modpathol.2011.217

Mutations of the tumor-suppressor gene ARID1A result in the loss of protein expression of the BRG-associated factor 250a (BAF250a), a large subunit of transcription-regulating Human SWI/SNF complexes, which have an important role in the con…

2008
Expression of class I histone deacetylases indicates poor prognosis in endometrioid subtypes of ovarian and endometrial carcinomas.
Neoplasia (New York, N.Y.) ·doi:10.1593/neo.08474

Histone deacetylase (HDAC) inhibitors are an emerging class of targeted cancer therapeutics, and little is known about HDAC expression in gynecologic malignancies. Therefore, we tested the hypothesis whether high-level expression of class 1…