Aim: To characterize magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) of histologically confirmed abdominal wall endometriosis (AWE) lesions and investigate the potential role of apparent diffusion coefficient (ADC) mea…
OBJECTIVE: Endometriosis is a benign condition driven by estrogen and inflammation in which endometrial-like tissue develops in ectopic locations. We aimed to determine whether non-steroidal agents acting on the WNT/beta-catenin signaling a…
Aim: To characterize MRI and diffusion-weighted imaging (DWI) of histologically confirmed abdominal wall endometriosis (AWE) lesions and investigate the potential role of apparent diffusion coefficient (ADC) measurements in preoperative dia…
OBJECTIVE: This study aimed to investigate the efficacy of metformin and ganirelix on subcutaneous endometriotic tissues created in an experimental mouse model. MATERIALS AND METHODS: Five groups were formed with eight animals in each grou…
OBJECTIVE: Currently, medical and surgical treatment options for endometriosis are limited due to suboptimal efficacy, and also safety and tolerance issues. Long-term use of gonadotrophin-releasing hormone analogs, androgenes, and the danaz…
Study objectiveTo evaluate serum values of cluster of differentiation 95 (CD95/FAS), hypoxia-inducible factor 1-alpha (HIF-1α), and tyrosine kinase receptor 2 (Tie-2) as possible biomarkers of disease presence and severity in women with end…
We aimed to compare the effects of pazopanib, sunitinib, and sorafenib on endometriotic tissue morphology and histological characteristics as well as ovarian reserve in a rat model. Experimental endometriosis was established in 32 rats. The…
Introduction Mammalian target of rapamycin is a pathway to block apoptosis. Recent studies showed that the activity of mammalian target of rapamycin pathway increases in endometriotic lesions. Aim of the present study was to study the effec…