Yongdong Dai

No ORCID on file · 17 papers in corpus · active 2016-2026

Study types

  • article 12
  • other 4
  • preprint 1

Condition tags

  • mesh:D004715 14
  • endometriosis 13
  • infertility 8
  • chronic_pelvic_pain 1
  • endometrioma 1
  • adenomyosis 1
other 2026
Journal of advanced research ·doi:10.1016/j.jare.2026.02.030

INTRODUCTION: Adenomyosis, which affects > 20% of reproductive-age women, is a major cause of infertility. Defective decidualization of endometrial stromal cells (ESCs) is a key pathogenic feature of adenomyosis; however, the underlying red…

article 2025
Advanced science (Weinheim, Baden-Wurttemberg, Germany) ·doi:10.1002/advs.202505656

We aimed to examine abnormal oxidative lipid levels and their related mechanisms in EM-associated infertility. Through liquid chromatography tandem mass spectrometry analysis, decreased levels of epoxyeicosatrienoic acids (EETs), which have…

other 2025
Human Reproduction ·doi:10.1093/humrep/deae247

STUDY QUESTION: What molecular mechanisms underlie the decline in ovarian reserve as the number and quality of oocytes decrease in patients with ovarian endometriomas (OEM)? SUMMARY ANSWER: Elevated expression of the let-7 micro(mi)RNAs in…

article 2024
Clinical and translational medicine ·doi:10.1002/ctm2.1564

Abstract Defective decidualization of endometrial stromal cells (ESCs) in endometriosis (EM) patients leads to inadequate endometrial receptivity and EM‐associated infertility. Hypoxia is an inevitable pathological process of EM and partici…

article 2023
The Journal of Pathology ·doi:10.1002/path.6079

Endometriosis is a common gynecological disorder that causes female infertility. Our recent research found that excessive oxidative stress in ovaries of endometriosis patients induced senescence of cumulus granulosa cells. Here, we analyzed…

article 2022
Endocrinology ·doi:10.1210/endocr/bqac210

The mechanism by which endometriosis, a common gynecological disease characterized by chronic pelvic pain and infertility, causes infertility remains elusive. Luteinized unruptured follicle syndrome, the most common type of ovulatory dysfun…

other 2022
Frontiers in endocrinology ·doi:10.3389/fendo.2022.825934

The outcomes of in vitro fertilization (IVF) for endometriotic women are significantly worse than for patients without ovarian endometriosis (OEM), as shown by fewer retrieved oocytes. However, the exact pathophysiological mechanism is stil…

article 2022
Journal of reproductive immunology ·doi:10.1016/j.jri.2022.103649
article 2022
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1007/s43032-021-00562-x
article 2021
Molecular medicine reports ·doi:10.3892/mmr.2021.12276

The pathological expression and function of lactate dehydrogenase A (LDHA), a key enzyme that converts pyruvate into lactic acid during glycolysis, remains unknown in endometriosis. In the present study, LDHA expression in tissue samples wa…

article 2020
Redox biology ·doi:10.1016/j.redox.2020.101431

Endometriosis an important cause of female infertility and seriously impact physical and psychological health of patients. Endometriosis is now considered to be a public health problem that deserves in-depth investigation, especially the et…

preprint 2020
·doi:10.21203/rs.3.rs-72780/v1
article 2019
Cell death & disease ·doi:10.1038/s41419-019-1395-6

Endometriosis is associated with benign but adversely developed cysts in the extrauterine environment. The oxidative imbalanced environment induces DNA damage and affects cell cycle progression of endometrial stromal cells (ESCs) and endome…

article 2018
Endocrinology ·doi:10.1210/en.2017-03227

Hypoxia plays a vital role in the progression of endometriosis. Additionally, integrin-mediated aberrant adhesion is also essential for establishment of endometriotic lesions. In this study, we sought to determine the function of hypoxia in…

article 2017
article 2017
Biology of reproduction ·doi:10.1093/biolre/iox140

To elucidate whether the endometriotic cells of endometriomas synthesize transforming growth factor beta1 (TGF-beta1) and understand how it affects surrounding ovarian tissue. We collected biopsies of the cystic walls from 42 endometriomas …

other 2016
Human Reproduction ·doi:10.1093/humrep/dew058

STUDY QUESTION: Are endometriotic mesenchymal stem cells (Ecto-MSCs) involved in the fibrosis of ovarian endometrioma? SUMMARY ANSWER: Ecto-MSCs enhanced the fibrotic behavior of stromal cells in ovarian endometrioma through the Wnt/β-cate…