Acute severe joint pain is a major symptom in gouty arthritis (GA), and its adequate treatment represents an unmet medical need. Mrgprb2, a specific mast cell receptor, has been implicated in the generation of chronic pain by mobilizing mas…
BACKGROUND: Uterine prolapse (UP), a subtype of pelvic organ prolapse (POP), frequently coexists with urinary tract infections (UTIs) and lower urinary tract symptoms (LUTS), including urinary frequency (UF), urinary incontinence (UI), and …
This research aimed to determine the predictive value of a combined diagnosis of serum platelet endothelial cell adhesion molecule-1 (PECAM-1) and placental growth factor (PLGF) levels, gut microbiota count, and uterine artery Doppler ultra…
Endometriosis (EMs)-related infertility commonly has decreased endometrial receptivity and normal decidualization is the basis for establishing and maintaining endometrial receptivity. However, the potential molecular regulatory mechanisms …
STUDY OBJECTIVE: This study aimed to observe and quantitatively analyze the morphology and distribution of uterine nerve fibers using fluorescence micro-optical sectioning tomography (fMOST). The goal was to provide an accurate morphologica…
IMPORTANCE: A growing number of children are conceived with assisted reproductive technology (ART). However, there is a lack of studies systematically analyzing the genetic landscape of live-born children conceived through ART who need inte…
BACKGROUND: Abdominal wall desmoid-type fibromatoses (AWDF) are occasionally encountered in clinical work, but related CT reports are rare, and most cases were misdiagnosed as malignant tumors. OBJECTIVE: We aimed to determine the diagnost…
BACKGROUND: To date, there is no consensus on whether intrauterine insemination (IUI) treatment is required in young patients with diminished ovarian reserve (DOR). Pregnancy outcomes in young DOR patients undergoing IUI are controversial. …
The AT-rich Interactive Domain 1A (ARID1A) is one of the most frequently mutated genes in gastric cancer. Here, we found that genetic variants in noncoding regions of ARID1A associated with altered protein levels by target sequencing. Notab…
Objective To investigate the effect of different dosages and different treatment methods of mifepristone in rat's endometriosis(EMs). Methods A total of 79 rats were selected to establishment of models of EMs, and were randomly divid…