McCracken R

No ORCID on file · 3 papers in corpus · active 1989-1991

Study types

  • article 2
1991
Bone matrix constituents stimulate interleukin-1 release from human blood mononuclear cells.
The Journal of clinical investigation ·doi:10.1172/jci114975

To test the hypothesis that mononuclear cells are stimulated to release interleukin 1 (IL-1) by bone fragments released in the bone microenvironment during the remodeling cycle, we have investigated the effects of bone matrix and some of it…

article 1991
Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.88.12.5134

To determine whether mononuclear cell secretory products contribute to the changes in bone turnover that characterize the development of postmenopausal osteoporosis, we evaluated the effects of oophorectomy and subsequent estrogen replaceme…

article 1989
Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.86.7.2398

In previous studies, we showed that blood monocyte elaboration of interleukin 1 (IL-1), a known stimulator of bone resorption, was higher in osteoporotic patients with rapid bone turnover than in those with slow turnover and in nonosteoporo…