Robert E. Pacifici

ORCID: 0000-0003-1465-362X · 2 papers in corpus · active 1989-1991

Study types

  • article 2
article 1991
Effect of surgical menopause and estrogen replacement on cytokine release from human blood mononuclear cells.
Proceedings of the National Academy of Sciences of the United States of America ·doi:10.1073/pnas.88.12.5134

To determine whether mononuclear cell secretory products contribute to the changes in bone turnover that characterize the development of postmenopausal osteoporosis, we evaluated the effects of oophorectomy and subsequent estrogen replaceme…

article 1989
Ovarian steroid treatment blocks a postmenopausal increase in blood monocyte interleukin 1 release.
·doi:10.1073/pnas.86.7.2398

In previous studies, we showed that blood monocyte elaboration of interleukin 1 (IL-1), a known stimulator of bone resorption, was higher in osteoporotic patients with rapid bone turnover than in those with slow turnover and in nonosteoporo…