Skupin-Mrugalska P

No ORCID on file · 2 papers in corpus · active 2021-2024
2024
Cancer cell international ·doi:10.1186/s12935-024-03469-0

BackgroundOlaparib is a PARP inhibitor inducing synthetic lethality in tumors with deficient homologous recombination (HRD) caused by BRCA1/2 mutations. The FDA has approved monotherapy for first-line platinum-sensitive, recurrent high-grad…

2021
Cancers ·doi:10.3390/cancers13164178

Despite the increasing development of medicine, ovarian cancer is still a high-risk, metastatic disease that is often diagnosed at a late stage. In addition, difficulties in its treatment are associated with high resistance to chemotherapy …