Zurakowski D

IntroductionChronic ocular pain (COP) is a widespread pain condition that presents clinical challenges, has heterologous and overlapping etiologies across patients, and can have a debilitating effect on quality of life. It can manifest with…

SignificanceQuantitative measurement of perisurgical brain function may provide insights into the processes contributing to acute and chronic postsurgical pain.AimWe evaluate the hemodynamic changes in the prefrontal cortex (medial frontopo…

IntroductionQuantitative sensory testing (QST) is often used to understand the perceptual basis of acute and chronic conditions, including pain. As the need grows for developing a mechanistic understanding of neurological pathways underlyin…

Endometriosis is a debilitating disease characterized by the growth of ectopic endometrial tissue. It is widely accepted that angiogenesis plays an integral part in the establishment and growth of endometriotic lesions. Recent data from a v…

In a prospective, blinded, longitudinal study MMP-2, MMP-9, and MMP-9/neutrophil gelatinase-associated lipocalin were significantly more likely to be detected in the urine of patients with endometriosis than in controls.

ObjectiveTo determine whether nonsteroidal antiinflammatory drugs (NSAIDs) affect the establishment and progression of endometriotic lesions in a murine model.DesignPharmacologic intervention in a surgically induced murine model of abdomina…