Sushmita Sen
No ORCID on file
· 15 papers in corpus
· active 2020-2024
Study types
- article 6
- preprint 4
- dataset 3
- meta-analysis 1
- other 1
Condition tags
- endometriosis 12
- infertility 8
- mesh:D004715 5
- adenomyosis 3
- dysmenorrhea 2
- chronic_pelvic_pain 1
Top journals
Frequent coauthors
other
2024
Existing medical treatments for endometriosis-related pain are often ineffective, underscoring the need for new therapeutic strategies. In this study, we applied a computational drug repurposing pipeline to stratified and unstratified disea…
article
2023
Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Herein, we characterize variation in DNA methylation (DNAm) and its association with menstrual cycle phase, endometriosis, and genetic variants t…
meta-analysis
2023
Endometriosis is a common condition associated with debilitating pelvic pain and infertility. A genome-wide association study meta-analysis, including 60,674 cases and 701,926 controls of European and East Asian descent, identified 42 genom…
dataset
2022
Additional file 1: Table S1. Samples used in the study. Endo: endometriosis; PE: proliferative; SE: secretory: MSE: mid secretory, LSE: late secretory; N/A: not applicable.
dataset
2022
Additional file 2: Table S2. CyTOF panels used in the study. Left: broad panel, right: focused panel.
dataset
2022
Additional file 9: Table S3. Expression of the significant markers between endometriosis and controls in all cell types in endometriosis versus controls from the focused panel. Significant values are highlighted in grey. Endo: endometriosis…
preprint
2022
Abstract Endometriosis is a common, inflammatory pain disorder comprised of disease in the pelvis and abnormal uterine lining and ovarian function that affects ∼200 million women of reproductive age worldwide and up to 50% of those with pel…
article
2022
Abstract Background Endometriosis is a chronic, estrogen-dependent disorder where inflammation contributes to disease-associated symptoms of pelvic pain and infertility. Immune dysfunction includes insufficient immune lesion clearance, a pr…
preprint
2022
Abstract Background Endometriosis is a chronic, estrogen-dependent disorder where inflammation contributes to disease-associated symptoms of pelvic pain and infertility. Immune dysfunction includes insufficient immune lesion clearance, a pr…
preprint
2022
Abstract Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Identifying biologic and genetic effects on DNA methylation (DNAm) in endometrium increases understanding of mechanisms that influence g…
article
2022
RESEARCH QUESTION: Adenomyosis is a common uterine disorder of uncertain causes. Can transcriptomic analyses of the endometrium and myometrium reveal potential mechanisms underlying adenomyosis pathogenesis? DESIGN: Transcriptomic profiles …
article
2022
The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has yet to be …
preprint
2021
Abstract The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has y…
article
2020
article
2020
Adenomyosis is a prevalent, estrogen-dependent uterine disorder wherein endometrial cells are abnormally present in the myometrium and are surrounded by hyperplastic/hypertrophic smooth muscle. Its etiology is unclear, although endometrial …