Idit Kosti

No ORCID on file · 6 papers in corpus · active 2021-2024

Study types

  • preprint 3
  • article 2
  • other 1

Condition tags

  • endometriosis 6
  • infertility 5
  • mesh:D004715 2
  • dysmenorrhea 1
  • chronic_pelvic_pain 1
other 2024
iScience ·doi:10.1016/j.isci.2024.109388

Existing medical treatments for endometriosis-related pain are often ineffective, underscoring the need for new therapeutic strategies. In this study, we applied a computational drug repurposing pipeline to stratified and unstratified disea…

article 2023
Communications biology ·doi:10.1038/s42003-023-05070-z

Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Herein, we characterize variation in DNA methylation (DNAm) and its association with menstrual cycle phase, endometriosis, and genetic variants t…

preprint 2022
·doi:10.1101/2022.12.20.22283736

Abstract Endometriosis is a common, inflammatory pain disorder comprised of disease in the pelvis and abnormal uterine lining and ovarian function that affects ∼200 million women of reproductive age worldwide and up to 50% of those with pel…

preprint 2022
·doi:10.1101/2022.11.27.518106

Abstract Endometriosis is a leading cause of pain and infertility affecting millions of women globally. Identifying biologic and genetic effects on DNA methylation (DNAm) in endometrium increases understanding of mechanisms that influence g…

article 2022
Frontiers in immunology ·doi:10.3389/fimmu.2021.788315

The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has yet to be …

preprint 2021
·doi:10.1101/2021.08.27.457966

Abstract The uterine lining (endometrium) exhibits a pro-inflammatory phenotype in women with endometriosis, resulting in pain, infertility, and poor pregnancy outcomes. The full complement of cell types contributing to this phenotype has y…