J C Irwin

No ORCID on file · 4 papers in corpus · active 1994-2016

Study types

  • article 4

Condition tags

  • endometriosis 4
  • infertility 2
article 2016
Aberrant Endometrial DNA Methylome and Associated Gene Expression in Women with Endometriosis
Biology of reproduction ·doi:10.1095/biolreprod.116.140434

Endometriosis is an estrogen-dependent, progesterone-resistant disorder largely derived from retrograde transplantation of menstrual tissue/cells into the pelvis, eliciting an inflammatory response, pelvic pain, and infertility. Eutopic end…

article 2012
Ectopic uterine tissue as a chronic pain generator
Neuroscience ·doi:10.1016/j.neuroscience.2012.08.033
article 2011
Nuclear Receptor, Coregulator Signaling, and Chromatin Remodeling Pathways Suggest Involvement of the Epigenome in the Steroid Hormone Response of Endometrium and Abnormalities in Endometriosis
Reproductive sciences (Thousand Oaks, Calif.) ·doi:10.1177/1933719111415546
article 1994
The insulin-like growth factor system in human peritoneal fluid: its effects on endometrial stromal cells and its potential relevance to endometriosis.
The Journal of clinical endocrinology and metabolism ·doi:10.1210/jcem.79.5.7525631

Peritoneal fluid (PF) lines the abdomen and pelvis and is believed to contain growth factors that stimulate endometriosis, a benign gynecological condition associated with pelvic pain and infertility, in which endometrial cells proliferate …