Jon D. Levine

ORCID: 0000-0003-0681-5545 · 5 papers in corpus · active 2012-2014

Study types

  • article 4
  • other 1

Condition tags

  • endometriosis 5
  • chronic_pelvic_pain 1
article 2014
Impact of surgical excision of lesions on pain in a rat model of endometriosis
European journal of pain (London, England) ·doi:10.1002/ejp.527

BACKGROUND: Chronic pain is the most common and disabling feature of endometriosis. Surgical excision of endometriosis lesions provides relief but pain relapse is common. Studies in a preclinical model of endometriosis might help to unravel…

article 2014
Role of nociceptor estrogen receptor GPR30 in a rat model of endometriosis pain
Pain ·doi:10.1016/j.pain.2014.09.035

Endometriosis, the most common cause of chronic pelvic pain, is an estrogen-dependent disease in which classic estrogen receptors (ERα, ERβ) play an important role. Although recent evidence suggests that the novel G protein-coupled estrogen…

article 2014
Screening the Role of Pronociceptive Molecules in a Rodent Model of Endometriosis Pain
The journal of pain ·doi:10.1016/j.jpain.2014.04.002
other 2013
Vascular endothelial cells mediate mechanical stimulation-induced enhancement of endothelin hyperalgesia via activation of P2X2/3 receptors on nociceptors
The Journal of neuroscience : the official journal of the Society for Neuroscience ·doi:10.1523/JNEUROSCI.3229-12.2013

Endothelin-1 (ET-1) is unique among a broad range of hyperalgesic agents in that it induces hyperalgesia in rats that is markedly enhanced by repeated mechanical stimulation at the site of administration. Antagonists to the ET-1 receptors, …

article 2012
Ectopic uterine tissue as a chronic pain generator
Neuroscience ·doi:10.1016/j.neuroscience.2012.08.033