Hsieh TH

No ORCID on file · 14 papers in corpus · active 2010-2023

Study types

  • article 10
  • other 1

Condition tags

  • endometriosis 11
  • endometrioma 2
article 2023
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2023.114500

Endometriosis is a common disease in women and may be one of the factors that induces malignant epithelial ovarian tumors. Previous studies suggested that endometriosis is related to ARID1A mutation mediating the expression of HDAC6, but th…

article 2021
The Journal of clinical endocrinology and metabolism ·doi:10.1210/clinem/dgab045

CONTEXT: Small extracellular vesicles (sEVs) have emerged as modulators of the disease microenvironment, thereby supporting disease progression. However, the potential role of EVs and their content to the pathophysiology of endometriosis re…

other 2019
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie ·doi:10.1016/j.biopha.2019.109105

Endometriosis is considered a high risk factor for the development of ovarian carcinoma, including clear cell and endometrioid malignancies. The mechanism by which endometriosis-associated ovarian cancer (EAOC) avoids anti-tumor immune surv…

article 2018
Oncology reports ·doi:10.3892/or.2018.6779

Ovarian cancer is the one of the most lethal gynecological cancer types. MicroRNAs (miRs) are noncoding RNAs that modulate the translation of their target mRNAs via binding to a complementary sequence in the target 3' untranslated region, a…

2017
Scientific reports ·doi:10.1038/s41598-017-00286-6

Phthalate, an environmental toxin, has been considered as an endocrine-disrupting chemical. Growing evidence has demonstrated links between endocrine-disrupting chemicals, tissue development, and reproductive physiology, but the mechanisms …

article 2016
International journal of cancer ·doi:10.1002/ijc.30591

Ovarian carcinosarcoma cancer is the most lethal form of gynecological malignancy, but the pathogenesis and biological function for this ovarian cancer remain unknown. We establishment the transgenic mouse model of K‐ras G12D p53 loxP/loxP …

article 2016
Biology of reproduction ·doi:10.1095/biolreprod.115.133330

Endometriosis is the hormone-dependent product of endometrial tissue found outside the uterus. Recently, micro-RNAs (miRNAs) were shown to play a role in endometriotic lesion development. However, the mechanism of steroid hormones responsib…

article 2016
Journal of molecular medicine (Berlin, Germany) ·doi:10.1007/s00109-016-1395-2

UnlabelledRecent molecular and pathological studies suggest that endometriosis may serve as a precursor of ovarian cancer (endometriosis-associated ovarian cancer, EAOC), especially of the endometrioid and clear cell subtypes. Accordingly, …

article 2013
The Journal of Pathology ·doi:10.1002/path.4295

It is believed that endometrial miRNAs contribute to the aetiology of endometriosis in stem cells; however, the mechanisms remain unclear. Here we collected serum samples from patients with or without endometriosis and characterized the miR…

article 2013
The American journal of pathology ·doi:10.1016/j.ajpath.2013.10.023

Immune dysregulation may be involved in the development of endometriosis. The anti-inflammatory cytokine IL-10 plays an important role in eliminating unwanted cells and cellular debris in a silent way. We investigated the modulatory role of…

2012
PloS one ·doi:10.1371/journal.pone.0042750

Environmental hormones play important roles in regulating the expression of genes involved in cell proliferation, drug resistance, and breast cancer risk; however, their precise role in human breast cancer cells during cancer progression re…

2012
The Kaohsiung journal of medical sciences ·doi:10.1016/j.kjms.2012.05.006

Phthalates--substances used in the manufacture of plastics--are considered as possible human carcinogens and tumor-promoting agents. The worldwide annual production of plastics surpassed 300 million tons in 2010. Plastics are an indispensab…

article 2011
Fertility and sterility ·doi:10.1016/j.fertnstert.2011.06.041

ObjectiveTo elucidate the role of interleukin-1β (IL-1β) on cyclooxygenase-2 (COX-2) expression and invasion of endometrioma-derived ectopic endometrial mesenchymal stem cells (EN-MSCs) and to develop an organoid method to study the invasiv…

article 2010
Fertility and sterility ·doi:10.1016/j.fertnstert.2010.09.064

ObjectiveTo elucidate the role of endometrial stem-progenitor cells in the etiology of endometriosis and to develop an animal model to study the invasion ability of endometrial cells.DesignGene expression and cell function studies were desi…