Yang H

Endometritis is a common reproductive disorder in dairy cows, with antibiotics being the primary treatment option. However, the overuse of antibiotics has contributed to the growing problem of antimicrobial resistance. Antimicrobial peptide…

IntroductionThe burden of gynaecological diseases is increasing globally, affecting women's health, quality of life and fertility. Improving the quality of gynaecological care will enhance patient recovery and improve outcomes of gynaecolog…

Women's reproductive health plays a pivotal role in both longevity and the aging process. We conduct Mendelian randomization (MR) and observational analyses to investigate these relationships. Univariate MR analyses reveal that older age at…

Small cell neuroendocrine carcinoma of the cervix (SCNEC) is a rare and highly aggressive malignancy with a poor prognosis. We report the case of a 36-year-old nulliparous woman with a history of HPV-18 infection and repeated cytology showi…

This review article focuses on the role of choline in ovarian follicular development, regulated by nutrient-epigenetic interactions. Choline, a key feed additive, participates in DNA methylation and steroid hormone synthesis via its methyl …

The lack of accurate understanding of cellular physiology and pathophysiology during the WOI constitutes the major obstacle to correct diagnosis and treatment for patients with recurrent implantation failure (RIF). The role of cilia as one …

BackgroundIntussusception is the leading cause of acute abdominal conditions in infants, yet it is frequently under-recognised in those younger than 3 months, potentially resulting in serious complications such as bowel necrosis, peritoniti…

OBJECTIVE: To investigate the correlation between preoperative pathologic characteristics and the risk of postoperative recurrence in endometriosis (EMs) patients, and to develop a clinical predictive model. METHODS: A retrospective analys…

Endometriosis, a complex gynecological disorder characterized by aberrant growth of endometrial tissue outside the uterine cavity, poses a significant challenge to women's health. Emerging evidence implicates environmental pollutants, parti…

ObjectivesWhether diverse metabolic statuses within a similar body mass index (BMI) category associate with different in vitro fertilization (IVF) outcomes.DesignA retrospective cohort study.SettingWenzhou, Zhengjiang Province, China.Popula…

Gastric cancer (GC) is the fifth most common malignant tumor worldwide. Surgical resection remains the primary treatment for GC, with laparoscopic surgery recommended by several international guidelines. Due to complex perigastric vessels, …

OBJECTIVE: With the rising frequency and earlier onset of endometrial cancer (EC), improved surgical skills have emerged as a priority. The objective of this study was to determine the effectiveness and safety of transumbilical laparoendosc…

Study questionIs there an association between changes in endometrial thickness (EMT) following progesterone administration and pregnancy outcomes in frozen-thawed embryo transfers (FETs) at Day 3 (D3) and blastocyst stages?Summary answerEnd…

Endometrium plays a crucial role in embryonic growth and development. Endometrial-related diseases, such as endometritis, endometriosis, endometrial cancer, and intrauterine adhesions, hurt fertility and women's health. At present, these di…

OBJECTIVE: Utilizing the Global Burden of Disease (GBD) 2021 dataset, this study analyzed temporal trends (1990-2021) and age-period-cohort patterns of endometriosis-related infertility burden in China versus globally. By employing joinpoin…

Abstract Aim Shixiao San, composed of Pollen Typha and Faeces Trogopterori, is a traditional Chinese medicine used for the the treatment of endometriosis. Jiawei Shixiao San is a modified formula derived from Shixiao San, adding with Sang…

Single and multiple endometrial polyps (EP) are common gynecological conditions with differing recurrence rates, influencing clinical treatment decisions. This study aimed to characterize the reproductive tract microbiome in both subtypes t…

ObjectivesWe aimed to determine the prevalence of female infertility in 204 countries and territories from 1990 to 2019.DesignWe evaluated the female infertility global burden between 1990 and 2019 in this systematic study.MaterialsThe Glob…

OBJECTIVE: To evaluate whether the timing of adenomyomectomy within the menstrual cycle influences outcomes in patients with adenomyosis, and to assess whether surgery performed during the secretory phase offers clinical advantages over the…

BackgroundTo assess the utility of the TCGA molecular classification of endometrial cancer in a well-annotated, moderately sized, consecutive cohort of Chinese patients with ovarian clear cell carcinoma (OCCC).MethodsWe performed DNA sequen…

Polycystic ovary syndrome (PCOS) affects reproductive and cardiometabolic health, yet its pathogenesis remains unclear. Emerging evidence links hemoglobin levels to metabolic disorders, suggesting a potential role in PCOS development. Here,…

Phthalate esters (PAEs), frequently detected in various environmental media, are associated with multiple health issues, particularly reproductive toxicity. This study employed molecular docking and molecular dynamics simulations to investi…

BACKGROUND: Endometriosis (EMS) is a difficult gynecological disease to cure. Frizzled-7 (FZD7) has been shown to be associated with the development of EMS, but its specific mechanism remains unclarified. This study aims to explore the role…

Fallopian tube carcinoma has a rare incidence and dismal prognosis. Sister Mary Joseph's nodule is an intra-abdominal tumor that metastasizes to the umbilicus. To date, fewer than 10 cases of fallopian tube carcinoma with Sister Mary Joseph…