Lerner TG

No ORCID on file · 9 papers in corpus · active 2011-2012

Study types

  • article 8
  • other 1

Condition tags

  • endometriosis 9
  • infertility 6
article 2012
Fertility and sterility ·doi:10.1016/j.fertnstert.2012.01.125

ObjectiveTo consider a possible cumulative effect of two genetic polymorphisms (FOXP3 C-2383T/rs3761549 and FCRL3 C-169T/rs7528684) that were previously shown to be associated with endometriosis.DesignGenetic association study.SettingHuman …

article 2012
Human immunology ·doi:10.1016/j.humimm.2012.08.008

IntroductionAn aberrant immunologic mechanism has been suggested to be involved in the pathogenesis of endometriosis. Nuclear factor-kB (NF-kB) plays a key role in the immune and inflammatory response and modulates cell proliferation, apopt…

article 2011
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia ·doi:10.1590/s0100-72032011000100006

PURPOSE: to evaluate the frequency of TP53 codon 72 polymorphism in infertile women with endometriosis, women with idiopathic infertility, controls and its relation to the disease. METHODS: a case-control study that included 198 infertile w…

article 2011
International journal of immunogenetics ·doi:10.1111/j.1744-313x.2011.01000.x

An autoimmune aetiology has been suggested for endometriosis mostly on the basis of an increased prevalence of autoimmune diseases in affected women. Cytotoxic T lymphocyte antigen (CTLA) 4 gene is recognized as a primary determinant for au…

article 2011
Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia

PURPOSE: to evaluate the frequency of VDR gene polymorphism Fok1 in infertile women with endometriosis and Control and its relation to the disease. METHODS: a case-control study that included 147 infertile women with endometriosis and 154 f…

article 2011
Human immunology ·doi:10.1016/j.humimm.2011.01.006

An aberrant immunologic mechanism has been suggested to be involved in the pathogenesis of endometriosis. Genetic alterations in the vitamin D receptor gene (VDR) may lead to important defects in gene activation that principally affect immu…

article 2011
Human immunology ·doi:10.1016/j.humimm.2011.05.005

An aberrant immunologic mechanism has been suggested to be involved in the pathogenesis of endometriosis. Fc receptor-like 3 gene (FCRL3) has been proposed as a novel autoimmune predisposing factor. The authors have hypothesized a possible …

article 2011
Acta obstetricia et gynecologica Scandinavica ·doi:10.1111/j.1600-0412.2011.01086.x

OBJECTIVE: To evaluate PAI-1 genotypes in a group of infertile women with or without endometriosis and control subjects. DESIGN: Case-control study. SETTING: Human Reproduction Center of Medicina do ABC Faculty. POPULATION: One hundred and …

other 2011
Scandinavian journal of immunology ·doi:10.1111/j.1365-3083.2011.02616.x

Many theories have been proposed to explain the development of endometriosis, and recently, autoimmune aetiology has been suggested. Besides, it is well known that endometriosis, especially the advanced disease, may impair fertility. B lymp…