Annemiek Nap

Research question: What is the current time to diagnosis among patients with endometriosis in the Netherlands, and what factors influence this time? Design: A retrospective questionnaire study was conducted in 11 hospitals in the Netherland…

OBJECTIVE: To assess the prevalence of surgically confirmed endometriosis among assigned-female-at-birth (AFAB) transgender and gender diverse (TGD) individuals undergoing laparoscopic pelvic surgery. DESIGN: Retrospective multicenter coho…

STUDY QUESTION: How can we best achieve tissue segmentation and cell counting of multichannel-stained endometriosis sections to understand tissue composition? SUMMARY ANSWER: A combination of a machine learning-based tissue analysis softwa…

STUDY QUESTION: How is endometriosis care organized at the primary, secondary, and tertiary care levels in five high-income countries? SUMMARY ANSWER: In all countries under study, initiatives have been taken to provide endometriosis care …

RESEARCH QUESTION: What is the current time to diagnosis among patients with endometriosis in the Netherlands, and what factors influence this time? DESIGN: A retrospective questionnaire study was conducted in 11 hospitals in the Netherlan…

Endometriosis is the growth of endometrial-like tissue at non-uterine locations, primarily within the peritoneal cavity. The disease can have diverse presentations with superficial lesions, deep invading lesions and ovarian cysts (endometri…

Endometriosis is a chronic condition characterised by cyclic pain symptoms that often significantly affect health-related quality of life. Predominantly framed as a "woman's condition", current research overlooks the experiences of transgen…

Transgender and gender diverse (TGD) individuals assigned female at birth (AFAB) are greatly impacted by endometriosis, which can severely affect their quality of life. This group faces significant barriers to healthcare due to structural d…

INTRODUCTION: Endometriosis causes severe and chronic pain leading to impaired Health-Related Quality of Life (HRQoL). While endometriosis surgery does improve pain intensity, psychological factors have an important role in pain perception.…

OBJECTIVES: Endometriosis, an estrogen-dependent chronic inflammatory disease, can cause visceral pain. Owing to its chronic nature, treatment can be challenging and insufficient in reducing all symptoms despite adequate management. Spinal-…

• Endometriosis is associated with long diagnostic delay. • A smartphone app could help to speed up the diagnostic process. • The Q1.6 app is user-friendly and collects real-time data on one’s menstrual cycle. • It differentiates between pa…

STUDY QUESTION: Is it possible to establish an ex vivo endometriosis model using cryopreserved endometriotic tissue fragments? SUMMARY ANSWER: Cryopreserved endometriotic tissue fragments remain viable after thawing and during at least 3 da…

Currently, the optimal treatment to increase the chance of pregnancy and live births in patients with colorectal endometriosis and subfertility is unknown. Evidence suggests that that both surgery and in vitro fertilisation (IVF) or intracy…

BACKGROUND: Fibrosis is an important pathological feature of endometriotic lesions of all subtypes. Fibrosis is present in and around endometriotic lesions, and a central role in its development is played by myofibroblasts, which are cells …

BACKGROUND: Due to a heterogeneity of symptoms, a lack of an adequate diagnostic test, and a lack of awareness, diagnostic delay in endometriosis in primary care on average amounts to 35 months. AIM: To determine which interventions are mo…

BACKGROUND: Transgender and gender diverse (TGD) people embody social and health inequalities that disproportionately affect this community more than the cisgender population. Endometriosis is a chronic condition of the reproductive tract t…

Consequences of the shift from the use of non-invasive testing for diagnosis to screening purposes • As the high-throughput screening and sequencing become increasingly faster and affordable, that there will be a swell of commercial non-inv…

RESEARCH QUESTION: What is the feasibility of an anti-inflammatory diet in women diagnosed with endometriosis? DESIGN: Qualitative study using semi-structured focus groups and individual interviews among patients with endometriosis. Transcr…

Endometriosis is the most prevalent benign gynaecologic disease with invalidating effects on the quality of life and decreased economic productivity. As pharmacologic and surgical treatment are only partially effective, women look for self-…