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- endometriosis 5
- dysmenorrhea 2
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To compare the effects of chlormadinone acetate (CMA), dienogest (DNG) and drospirenone (DRSP) on prostaglandin biosynthesis in a human endometrial explants model.
Cytochrome P450 metabolism of arachidonic acid (AA) was investigated in human peritoneal macrophages which play a central role in chronic pelvic diseases in women (for example in endometriosis). The formation of eicosanoids other than prost…
Primary dysmenorrhea occurs mostly in young women with a painful bleeding pattern. In a recent study, 72% of 19-year-old women had light, 19% had medium to severe, and 8% had severe symptoms. Secondary dysmenorrhea means pathological organi…
Six patients suffering from endometriosis (Acosta stages I to III) were treated by luteinizing hormone-releasing hormone agonists (LHRH-A). In 3 of the 6 patients buserelin (Hoechst AG, FRG) was subcutaneously infused using an osmotic minip…